Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053367 | 0.77 | ASPH (0.49) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL27467197 | 0.76 | KMT2A (0.42) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL12466650 | 0.74 | TXNRD1 (0.40) | NPC1RAB9AMAPTCTSBTLR9 | |
| SCHEMBL16519973 | 0.73 | TDP1 (0.48) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL27669225 | 0.71 | ALDH1A1 (0.41) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL5087943 | 0.71 | VCAM1 (0.47) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL1917135 | 0.71 | MEN1 (0.44) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL126343 | 0.71 | PDE10A (0.51) | MEN1KMT2ARAB9AMAPTCTSB | |
| SCHEMBL30832623 | 0.71 | PDE10A (0.51) | MEN1KMT2ARAB9AMAPTCTSB | |
| SCHEMBL27944821 | 0.70 | MEN1 (0.43) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003026664-A1 | 2-PHENYLAMINO-4- (5-PYRAZOLYLAMINO) -PYRAMIDINE DERIVATIVES AS KINASE INHIBITORS, IN PARTICULAR, SRC KINASE INHIBITORS | BAYER CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |