SCHEMBL7053445

SCHEMBL7053445

Cc1ccc(-c2nc3ccccc3o2)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 1/20 0.61
KDM6A O15550 1/20 0.61
TOP2A P11388 1/20 0.58
KDM4E B2RXH2 7/20 0.56
HPGD P15428 7/20 0.56
MAPT P10636 7/20 0.56
ALDH1A1 P00352 6/20 0.56
USP2 O75604 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
ESR1 P03372 4/20 0.54
ESR2 Q92731 4/20 0.54
PTGS2 P35354 1/20 0.53
NPC1 O15118 6/20 0.53
RAB9A P51151 6/20 0.53
SMN1; SMN2 Q16637 5/20 0.53
POLB P06746 3/20 0.53
CASP3 P42574 1/20 0.53
SENP8 Q96LD8 1/20 0.53
SENP7 Q9BQF6 1/20 0.53
SENP6 Q9GZR1 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3134187 0.89 KDM6B (0.73) KDM6BKDM6ATOP2AKDM4EHPGD
SCHEMBL14085541 0.88 KDM6B (0.52) KDM6BKDM6ATOP2AKDM4EHPGD
SCHEMBL10039086 0.86 KDM4E (0.67) KDM6BKDM6AKDM4EHPGDMAPT
SCHEMBL17654013 0.84 KDM6B (0.79) KDM6BKDM6ATOP2AKDM4EHPGD
SCHEMBL30900831 0.84 KDM6B (0.79) KDM6BKDM6ATOP2AKDM4EHPGD
SCHEMBL1550348 0.83 TOP2A (0.79) KDM6BKDM6ATOP2AKDM4EHPGD
SCHEMBL1296601 0.83 KDM6B (0.78) KDM6BKDM6ATOP2AKDM4EHPGD
SCHEMBL12304263 0.83 KDM4E (0.62) KDM6BKDM6AKDM4EHPGDMAPT
SCHEMBL11696610 0.83 HPGD (0.55) KDM6BKDM6AKDM4EHPGDMAPT
SCHEMBL11869096 0.83 KDM4E (0.55) KDM6BKDM6AKDM4EHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9822164-B2 Labelling agent, and composition for labelling a protein, method for labelling a protein, and method for detecting a protein KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-11-21 US disclosed
US-9601704-B2 Organic light-emitting device and display apparatus CANON KABUSHIKI KAISHA (JP) 2017-03-21 US disclosed
US-9466804-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2016-10-11 US disclosed
US-20160121293-A1 LABELLING AGENT, AND COMPOSITION FOR LABELLING A PROTEIN, METHOD FOR LABELLING A PROTEIN, AND METHOD FOR DETECTING A PROTEIN KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-05-05 US disclosed
US-20150364703-A1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-12-17 US disclosed
US-20150357587-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150333279-A1 ORGANIC LIGHT-EMITTING ELEMENT AND DISPLAY APPARATUS SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-11-19 US disclosed
WO-2003018712-A1 ORGANIC LUMINESCENT COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME NEOVIEW CO., LTD. (KR) 2003-03-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160121293-A1 LABELLING AGENT, AND COMPOSITION FOR LABELLING A PROTEIN, METHOD FOR LABELLING A PROTEIN, AND METHOD FOR DETECTING A PROTEIN OR10J3, NR1H3, NR1H2 KDM6B 2897/4885KDM6A 2890/4885TOP2A 4287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.