Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | GNRHR | P30968 | 7/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1625246 | 0.90 | PTGER4 (0.65) | PTGER4MAPTGNRHRCA12CA1 | |
| SCHEMBL1625573 | 0.89 | PTGER4 (0.64) | PTGER4MAPTGNRHRCA12CA1 | |
| SCHEMBL27582816 | 0.89 | PTGER4 (0.57) | PTGER4MAPTTP53GNRHRCA12 | |
| SCHEMBL1625236 | 0.84 | PTGS2 (0.38) | PTGER4MAPTTP53CNR1CA12 | |
| SCHEMBL1625975 | 0.83 | CNR2 (0.35) | PTGER4MAPTTP53CA12CA1 | |
| SCHEMBL1626191 | 0.82 | PTGER4 (0.64) | PTGER4MAPTCA12CA1CA2 | |
| SCHEMBL1625674 | 0.82 | PTGER4 (0.64) | PTGER4MAPTTP53CA12CA1 | |
| SCHEMBL1625626 | 0.82 | CNR2 (0.35) | PTGER4MAPTTP53CA12CA1 | |
| SCHEMBL1626699 | 0.82 | PTGER4 (0.64) | PTGER4MAPTTP53GNRHRCA12 | |
| SCHEMBL1625530 | 0.82 | PTGER4 (0.37) | PTGER4MAPTTP53CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6710054-B2 | CONTAINING SULFONYLAMINOCARBONYL GROUPS; PROSTAGLANDIN INHIBITORS | PFIZER INC | 2004-03-23 | — | — | US | disclosed |