Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055336 | 0.80 | MAPT (0.43) | MAPTALDH1A1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL7053837 | 0.78 | MAPT (0.42) | MAPTALDH1A1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL444734 | 0.78 | MAPT (0.42) | MAPTALDH1A1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL4034128 | 0.78 | HCAR2 (0.62) | MAPTALDH1A1TP53HTTHCAR2 | |
| SCHEMBL7048303 | 0.77 | MAPT (0.41) | MAPTALDH1A1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL11899421 | 0.77 | NOTUM (0.43) | MAPTALDH1A1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL1536321 | 0.77 | CHRNA4 (0.52) | MAPTALDH1A1CYP1A2TP53HTT | |
| SCHEMBL16935060 | 0.77 | MAPT (0.41) | MAPTALDH1A1HSD17B10TP53HTT | |
| SCHEMBL20928812 | 0.75 | — | — | |
| SCHEMBL5285379 | 0.74 | LMNA (0.47) | MAPTALDH1A1CYP1A2CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |