Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CPA3 | P15088 | 2/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | CPA1 | P15085 | 4/20 | 0.49 |
| ▸ | ACE | P12821 | 4/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4838500 | 0.83 | MME (0.65) | MMECYP1A2CPA3FOLH1CPA1 | |
| SCHEMBL498453 | 0.83 | MME (0.65) | MMECYP1A2CPA3FOLH1CPA1 | |
| SCHEMBL3411005 | 0.81 | MME (0.58) | MMECYP1A2CPA3FOLH1CPA1 | |
| Hydrochloric Acid SCHEMBL7054010 | 0.81 | MME (0.62) | MMECYP1A2CPA3FOLH1CPA1 | |
| SCHEMBL25432477 | 0.79 | EPHX1 (0.58) | MMECYP1A2CPA3FOLH1CPA1 | |
| SCHEMBL5609028 | 0.79 | MME (0.56) | MMECYP1A2CPA3FOLH1CPA1 | |
| SCHEMBL8240623 | 0.79 | EPHX1 (0.58) | MMECYP1A2CPA3FOLH1CPA1 | |
| SCHEMBL2456064 | 0.79 | MME (0.56) | MMECYP1A2CPA3FOLH1CPA1 | |
| SCHEMBL8040411 | 0.78 | CYP1A2 (0.68) | MMECYP1A2CPA3FOLH1CPA1 | |
| SCHEMBL1586317 | 0.78 | MDM2 (0.61) | MMECYP1A2CPA3FOLH1CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030036532-A1 | Use of 2-phenylene diamine derivatives for the treatment of infections | JOMAA PHARMAKA GMBH (DE) | 2003-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036532-A1 | Use of 2-phenylene diamine derivatives for the treatment of infections | HRH2, ASPH, NQO2 | MME 1201/4885CYP1A2 91/4885CPA3 2845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.