Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.82 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.82 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.82 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | CNR2 | P34972 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052620 | 0.90 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| Hydrochloric Acid SCHEMBL7052441 | 0.90 | PDE4A (0.98) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL10852270 | 0.87 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL7055286 | 0.86 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL10855346 | 0.86 | ALDH1A1 (0.70) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL7051839 | 0.85 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL10850233 | 0.84 | ALDH1A1 (0.67) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL10849628 | 0.82 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL7057683 | 0.82 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL7051831 | 0.81 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841929-B1 | QUINOLONES AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LTD (GB) | 2003-05-07 | — | — | EP | claimed |
| EP-0841929-B1 | QUINOLONES AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LTD (GB) | 2003-05-07 | — | — | EP | disclosed |