⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28281978 | 0.89 | — | — | |
| SCHEMBL1710592 | 0.88 | — | — | |
| Phosphoric Acid SCHEMBL4952584 | 0.86 | — | — | |
| SCHEMBL28282096 | 0.85 | — | — | |
| SCHEMBL2411308 | 0.83 | — | — | |
| SCHEMBL22544221 | 0.83 | — | — | |
| SCHEMBL10339082 | 0.81 | SIRT2 (0.36) | — | |
| SCHEMBL6902692 | 0.81 | SIRT2 (0.36) | — | |
| SCHEMBL179683 | 0.81 | — | — | |
| SCHEMBL10871192 | 0.79 | SIRT2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126151-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-117126152-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-117069712-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117069713-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117024420-A | Glycolate oxidase inhibitors for use in the treatment of disease | 生物马林药物股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| US-20230088214-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2023-03-23 | — | — | US | disclosed |
| US-20230089374-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2023-03-23 | — | — | US | disclosed |
| US-20230079913-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2023-03-16 | — | — | US | disclosed |
| US-11384055-B2 | Glycolate oxidase inhibitors for the treatment of disease | BIOMARIN PHARMACEUTICAL INC. (US) | 2022-07-12 | — | — | US | disclosed |
| EP-3986863-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BioMarin Pharmaceutical Inc. (US) | 2022-04-27 | — | — | EP | disclosed |
| US-20030109744-A1 | PROCESS FOR PREPARING 3-HYDROXYESTERS FROM EPOXIDE DERIVATIVES | DAVY PROCESS TECHNOLOGY LTD. (GB) | 2003-06-12 | — | — | US | disclosed |
| EP-1304321-A2 | Process for preparing 3-Hydroxyesters from epoxide derivatives | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2003-04-23 | — | — | EP | disclosed |
| CN-1412173-A | Process for preparing 3-hydroxy ester from epoxide derivative | SAMSUNG ELECTRONICS CO LTD (KR) | 2003-04-23 | — | — | CN | disclosed |
| US-6465680-B2 | USING COBALT CATALYST AND PROMOTER | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2002-10-15 | — | — | US | disclosed |
| US-20020035290-A1 | Process for preparing malonate derivatives or beta -keto esters from epoxide derivatives | SAMSUNG ELECTRONICS CO., LTD. | 2002-03-21 | — | — | US | disclosed |
| CN-1330064-A | Method for producing malonate derivative or beta-ket-acid ester by epoxide derivative | SAMSUNG ELECTRONICS CO LTD (KR) | 2002-01-09 | — | — | CN | disclosed |
| US-5466838-A | Catalytic reaction of olefin with oxygen in the presence of aldehyde | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-11-14 | — | — | US | disclosed |
| EP-0540009-B1 | Process for producing epoxides | SUMITOMO CHEMICAL CO (JP) | 1995-08-30 | — | — | EP | disclosed |
| US-5367087-A | Process for producing epoxide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-11-22 | — | — | US | disclosed |
| EP-0540009-A1 | Process for producing epoxides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |