⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28282096 | 0.97 | — | — | |
| SCHEMBL28281978 | 0.89 | — | — | |
| SCHEMBL7054256 | 0.88 | — | — | |
| SCHEMBL15187187 | 0.87 | — | — | |
| Dimethyl Sulfoxide SCHEMBL10480705 | 0.87 | — | — | |
| SCHEMBL10870786 | 0.84 | SIRT2 (0.39) | — | |
| SCHEMBL10869899 | 0.84 | SIRT2 (0.39) | — | |
| SCHEMBL10873955 | 0.84 | SIRT2 (0.39) | — | |
| SCHEMBL10870865 | 0.84 | SIRT2 (0.39) | — | |
| SCHEMBL10871122 | 0.84 | SIRT2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029708-B2 | Alkoxy compounds for disease treatment | ACUCELA INC. (US) | 2024-07-09 | — | — | US | disclosed |
| US-12029708-B2 | Alkoxy compounds for disease treatment | ACUCELA INC. (US) | 2024-07-09 | — | — | US | disclosed |
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
| US-11446261-B2 | Alkoxy compounds for disease treatment | ACUCELA INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210077427-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2021-03-18 | — | — | US | disclosed |
| US-10639286-B2 | Alkoxy compounds for disease treatment | ACUCELA INC. (US) | 2020-05-05 | — | — | US | disclosed |
| US-20190183816-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2019-06-20 | — | — | US | disclosed |
| US-10188615-B2 | Alkoxy compounds for disease treatment | ACUCELA INC. (US) | 2019-01-29 | — | — | US | disclosed |
| US-20180177746-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2018-06-28 | — | — | US | disclosed |
| EP-0310321-B1 | Immunomodulatory azaspiranes | SMITHKLINE BEECHAM CORP (US) | 1994-11-30 | — | — | EP | disclosed |
| WO-1989002889-A1 | IMMUNOMODULATORY AZASPIRANES | SMITHKLINE BECKMAN CORPORATION (US) | 1989-04-06 | — | — | WO | disclosed |
| EP-0310321-A2 | Immunomodulatory azaspiranes | SMITHKLINE BEECHAM CORPORATION (US) | 1989-04-05 | — | — | EP | disclosed |
| US-4503204-A | CATALYST CONTAINING ALUMINUM, MAGENESIUM AND BARIUM, STRONTIUM OR CALCIUM | THE GENERAL TIRE & RUBBER COMPANY (US) | 1985-03-05 | — | — | US | disclosed |
| US-4355156-A | ALCOHOLATE CATALYST COMPONENT | THE GENERAL TIRE & RUBBER COMPANY (US) | 1982-10-19 | — | — | US | disclosed |
| US-4307218-A | TRANS- POLYBUTADIENE OR BUTADIENE- STYRENE COPOLYMER | THE GENERAL TIRE & RUBBER COMPANY (US) | 1981-12-22 | — | — | US | disclosed |
| US-4302568-A | POLYMERIZATION CATALYST COMPRISING A COMPLEX OF A GROUP 2A METAL ALCOHOLATE AND ALUMINUM AND MAGNESIUM COMPOUNDS | THE GENERAL TIRE & RUBBER CO. (US) | 1981-11-24 | — | — | US | disclosed |
| US-4297240-A | AND A POLYMERIZATION CATALYST MADE FROM ALKALINE METAL ALCOHOLATES AND ALKYL OR CYCLOALKYL ALUMINUM AND MAGNESIUM COMPOUNDS | THE GENERAL TIRE & RUBBER COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| US-4260519-A | POLYMERIZATION CATALYSTS | THE GENERAL TIRE & RUBBER COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4260712-A | USED IN COMPLEXES WITH A HYDROCARBYL LITHIUM COMPOUND AS A POLYMERIZATION CATALYST | THE GENERAL TIRE & RUBBER COMPANY (US) | 1981-04-07 | — | — | US | disclosed |