SCHEMBL7054320

SCHEMBL7054320

C[N]c1ccc(N(C)C)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.61
TSHR P16473 6/20 0.61
HSD17B10 Q99714 4/20 0.61
ALOX15 P16050 4/20 0.61
MAPK1 P28482 6/20 0.61
TP53 P04637 3/20 0.61
HIF1A Q16665 1/20 0.61
TDP1 Q9NUW8 5/20 0.56
CYP3A4 P08684 2/20 0.55
ADRA2A P08913 2/20 0.54
ADRA2B P18089 2/20 0.54
ADRA2C P18825 2/20 0.54
KMT2A Q03164 5/20 0.52
MEN1 O00255 4/20 0.52
NOS1 P29475 3/20 0.52
KDM4E B2RXH2 2/20 0.52
MAPT P10636 2/20 0.52
THRB P10828 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1405466 0.80 ALDH1A1 (0.81) ALDH1A1TSHRHSD17B10ALOX15MAPK1
SCHEMBL1405467 0.80 ALDH1A1 (0.81) ALDH1A1TSHRHSD17B10ALOX15MAPK1
SCHEMBL3217829 0.80 ALDH1A1 (0.81) ALDH1A1TSHRHSD17B10ALOX15MAPK1
SCHEMBL3217836 0.80 ALDH1A1 (0.81) ALDH1A1TSHRHSD17B10ALOX15MAPK1
SCHEMBL3217840 0.80 ALDH1A1 (0.81) ALDH1A1TSHRHSD17B10ALOX15MAPK1
SCHEMBL3184563 0.80 ALDH1A1 (0.65) ALDH1A1TSHRHSD17B10ALOX15MAPK1
SCHEMBL10038796 0.79 ALDH1A1 (0.64) ALDH1A1TSHRHSD17B10ALOX15MAPK1
SCHEMBL13647438 0.79 ALDH1A1 (0.64) ALDH1A1TSHRHSD17B10ALOX15MAPK1
SCHEMBL65261 0.78 ALDH1A1 (1.00) ALDH1A1TSHRHSD17B10ALOX15MAPK1
SCHEMBL1696969 0.78 MAPT (0.39) ALDH1A1TSHRHSD17B10MAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882715-B1 NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES KUREHA CHEMICAL IND CO LTD (JP) 2003-04-23 EP disclosed
US-6339045-B1 CAN BE USED IN A SMALL AMOUNT, SHOWING A GOOD SELECTIVITY BETWEEN CROP AND WEED, AND CAUSING NO PHYTOTOXICITY KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-01-15 US disclosed
EP-0882715-A1 NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-12-09 EP disclosed
EP-0248932-B1 PROCESS FOR PREPARING POLYAMIDES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-01-09 EP disclosed
EP-0177793-B1 PROCESS FOR PREPARING POLYAMIDES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1990-11-28 EP disclosed
US-4754016-A Process for preparing polyamide with organic phosphine/organic disulfide mixture condensing agent ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-06-28 US disclosed
EP-0248932-A1 Process for preparing polyamides Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-12-16 EP disclosed
US-4645823-A CORROSION RESISTANCE; NONTOXIC ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1987-02-24 US disclosed
EP-0177793-A2 Process for preparing polyamides Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-04-16 EP disclosed