SCHEMBL7054565

SCHEMBL7054565

CCCCCCCCCCCCCCCCCCCCC1=NCCO1

nearest known ligand 0.81

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.34
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.32
ALDH1A1 P00352 2/20 0.32
ACHE P22303 1/20 0.32
BACE1 P56817 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32
SCD O00767 1/20 0.32
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL959108 1.00 KCNH2 (0.34) KCNH2TSHRTHRBALDH1A1ACHE
SCHEMBL961102 1.00 KCNH2 (0.34) KCNH2TSHRTHRBALDH1A1ACHE
SCHEMBL7060405 1.00 KCNH2 (0.34) KCNH2TSHRTHRBALDH1A1ACHE
SCHEMBL8337997 1.00 KCNH2 (0.34) KCNH2TSHRTHRBALDH1A1ACHE
SCHEMBL7056733 1.00 KCNH2 (0.34) KCNH2TSHRTHRBALDH1A1ACHE
SCHEMBL7061452 1.00 KCNH2 (0.34) KCNH2TSHRTHRBALDH1A1ACHE
SCHEMBL7058385 1.00 KCNH2 (0.34) KCNH2TSHRTHRBALDH1A1ACHE
SCHEMBL2493950 1.00 KCNH2 (0.34) KCNH2TSHRTHRBALDH1A1ACHE
SCHEMBL7206068 1.00 KCNH2 (0.34) KCNH2TSHRTHRBALDH1A1ACHE
SCHEMBL7056094 1.00 KCNH2 (0.34) KCNH2TSHRTHRBALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116981758-A Thermally responsive brush polymers having a copolymer backbone and copolymer arms 英菲诺姆国际有限公司 2023-10-31 CN disclosed
CN-1128611-C Emulsified, water-in-oil type composition and skin cosmetic preparation KAO CORP (JP) 2003-11-26 CN disclosed
US-6610278-B2 Hardness not greater than 75 as measured by an Asker rubber-hardness tester type C1L; a porosity of at least 0.4; and an impact resistance of at least 5; excellent skin feel upon use and is not easily broken. KAO CORPORATION (JP) 2003-08-26 US disclosed
EP-0761202-B1 Emulsified, water-in-oil type composition and skin cosmetic preparation KAO CORP (JP) 2003-05-14 EP disclosed
US-6440429-B1 FRESH FEEL, NONSTICKY; HIGH MOLECULAR WEIGHT HYDROPHILIC POLYSILOXANE BLOCK POLYMERS; SILICONE OILS; STABILITY KAO CORPORATION (JP) 2002-08-27 US disclosed
CN-1150539-A Emulsified, water-in-oil type composition and skin cosmetic preparation KAO CORP (JP) 1997-05-28 CN disclosed
EP-0761202-A2 Emulsified, water-in-oil type composition and skin cosmetic preparation KAO CORPORATION (JP) 1997-03-12 EP disclosed
EP-0524612-B1 Modified silicone containing hair cosmetic KAO CORP (JP) 1996-03-06 EP disclosed
US-5472689-A Hair cosmetic composition containing a poly(N-acylalkyleneimine)-organopolysiloxane block or graft copolymer KAO CORPORATION (JP) 1995-12-05 US disclosed
EP-0524612-A2 Modified silicone containing hair cosmetic KAO CORPORATION (JP) 1993-01-27 EP disclosed