Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL959108 | 1.00 | KCNH2 (0.34) | KCNH2TSHRTHRBALDH1A1ACHE | |
| SCHEMBL961102 | 1.00 | KCNH2 (0.34) | KCNH2TSHRTHRBALDH1A1ACHE | |
| SCHEMBL7060405 | 1.00 | KCNH2 (0.34) | KCNH2TSHRTHRBALDH1A1ACHE | |
| SCHEMBL8337997 | 1.00 | KCNH2 (0.34) | KCNH2TSHRTHRBALDH1A1ACHE | |
| SCHEMBL7056733 | 1.00 | KCNH2 (0.34) | KCNH2TSHRTHRBALDH1A1ACHE | |
| SCHEMBL7061452 | 1.00 | KCNH2 (0.34) | KCNH2TSHRTHRBALDH1A1ACHE | |
| SCHEMBL7058385 | 1.00 | KCNH2 (0.34) | KCNH2TSHRTHRBALDH1A1ACHE | |
| SCHEMBL7206068 | 1.00 | KCNH2 (0.34) | KCNH2TSHRTHRBALDH1A1ACHE | |
| SCHEMBL7056094 | 1.00 | KCNH2 (0.34) | KCNH2TSHRTHRBALDH1A1ACHE | |
| SCHEMBL960613 | 1.00 | KCNH2 (0.34) | KCNH2TSHRTHRBALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621988-A | Endoglycosidase covalently modified by affinity fragment, preparation method thereof and application thereof in glycosylation modification of glycoprotein | 中国科学院上海药物研究所 | 2023-08-22 | — | — | CN | claimed |
| EP-2814489-B1 | COMPOSITIONS AND METHODS FOR THE MODULATION OF SPECIFIC AMIDASES FOR N-ACYLETHANOLAMINES FOR USE IN THE THERAPY OF INFLAMMATORY DISEASES | EPITECH GROUP S P A (IT) | 2017-08-23 | — | — | EP | claimed |
| US-9512091-B2 | Compositions and methods for the modulation of specific amidases for N-acylethanolamines for use in the therapy of inflammatory diseases | EPITECH GROUP S.R.L. (IT) | 2016-12-06 | — | — | US | claimed |
| US-20150057269-A1 | COMPOSITIONS AND METHODS FOR THE MODULATION OF SPECIFIC AMIDASES FOR N-ACYLETHANOLAMINES FOR USE IN THE THERAPY OF INFLAMMATORY DISEASES | EPITECH GROUP S.R.L. (IT) | 2015-02-26 | — | — | US | claimed |
| EP-2814489-A1 | COMPOSITIONS AND METHODS FOR THE MODULATION OF SPECIFIC AMIDASES FOR N-ACYLETHANOLAMINES FOR USE IN THE THERAPY OF INFLAMMATORY DISEASES | Epitech Group S.r.l. (IT) | 2014-12-24 | — | — | EP | claimed |
| WO-2013121449-A1 | COMPOSITIONS AND METHODS FOR THE MODULATION OF SPECIFIC AMIDASES FOR N-ACYLETHANOLAMINES FOR USE IN THE THERAPY OF INFLAMMATORY DISEASES | EPITECH GROUP S.R.L. (IT) | 2013-08-22 | — | — | WO | claimed |
| EP-4267708-B1 | THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS | INFINEUM INT LTD (GB) | 2025-07-02 | — | — | EP | disclosed |
| US-12281203-B2 | Thermally responsive brush polymers having a copolymer backbone and copolymer arms | INFINEUM INTERNATIONAL LIMITED (GB) | 2025-04-22 | — | — | US | disclosed |
| US-20240309155-A1 | Thermally Responsive Brush Polymers Having a Copolymer Backbone and Copolymer Arms | INFINEUM INTERNATIONAL LIMITED (GB) | 2024-09-19 | — | — | US | disclosed |
| EP-4267708-A1 | THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS | Infineum International Limited (GB) | 2023-11-01 | — | — | EP | disclosed |
| CN-116981758-A | Thermally responsive brush polymers having a copolymer backbone and copolymer arms | 英菲诺姆国际有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116621988-A | Endoglycosidase covalently modified by affinity fragment, preparation method thereof and application thereof in glycosylation modification of glycoprotein | 中国科学院上海药物研究所 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022136384-A1 | THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS | INFINEUM INTERNATIONAL LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |
| EP-0524612-A2 | Modified silicone containing hair cosmetic | KAO CORPORATION (JP) | 1993-01-27 | — | — | EP | disclosed |
| US-5153273-A | Amphiphilic macromonomer having polyethyleneimine derivative chain and production process thereof, as well as graft polymer having amphiphilic polyethyleneimine derivative chain as a graft chain and production process thereof | KOBAYASHI SHIRO (JP) | 1992-10-06 | — | — | US | disclosed |
| US-5030629-A | Transdermal Administration Of Cardiovascular Agents | THERAPEUTIC PATCH RESEARCH N.V. | 1991-07-09 | — | — | US | disclosed |
| US-4876249-A | TOPICAL; TRANSDERMAL, SYSTEMIC; FLUOCINOLINE ACETONIDE AND IMIDAZOLINE OR OXAZOLINE PENETRATION ENHANCER MIXTURE; THERAPEUTIC DRUGS | THERAPEUTIC PATCH RESEARCH N.V. | 1989-10-24 | — | — | US | disclosed |
| EP-0296199-A1 | HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE | RAJADHYAKSHA, Vithal J. (US) | 1988-12-28 | — | — | EP | disclosed |
| WO-1988004938-A1 | HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE | RAJADHYAKSHA VITHAL J (US) | 1988-07-14 | — | — | WO | disclosed |
| US-4540747-A | POLYOXAZOLINES AND OXAZINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057269-A1 | COMPOSITIONS AND METHODS FOR THE MODULATION OF SPECIFIC AMIDASES FOR N-ACYLETHANOLAMINES FOR USE IN THE THERAPY OF INFLAMMATORY DISEASES | NAAA, APEH, FAAH2 | KCNH2 2884/4885TSHR 2606/4885THRB 2949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.