Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.76 |
| ▸ | BACE1 | P56817 | 4/20 | 0.76 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.64 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7054733 | 1.00 | GSK3B (0.76) | GSK3BBACE1ABCG2MAOBSLC5A1 | |
| SCHEMBL527828 | 0.88 | GSK3B (0.80) | GSK3BBACE1ABCG2MAOBSLC5A1 | |
| SCHEMBL7999153 | 0.88 | GSK3B (0.83) | GSK3BBACE1ABCG2MAOBSLC5A1 | |
| SCHEMBL8740053 | 0.88 | GSK3B (0.80) | GSK3BBACE1ABCG2MAOBSLC5A1 | |
| SCHEMBL527827 | 0.88 | GSK3B (0.80) | GSK3BBACE1ABCG2MAOBSLC5A1 | |
| SCHEMBL7999149 | 0.88 | GSK3B (0.83) | GSK3BBACE1ABCG2MAOBSLC5A1 | |
| Hydrochloric Acid SCHEMBL7054738 | 0.86 | GSK3B (0.78) | GSK3BBACE1ABCG2MAOBSLC5A1 | |
| SCHEMBL8682717 | 0.85 | GSK3B (0.70) | GSK3BBACE1ABCG2MAOBMEN1 | |
| SCHEMBL8682715 | 0.85 | GSK3B (0.70) | GSK3BBACE1ABCG2MAOBMEN1 | |
| SCHEMBL9344834 | 0.85 | GSK3B (0.76) | GSK3BBACE1ABCG2MAOBSLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030036532-A1 | Use of 2-phenylene diamine derivatives for the treatment of infections | JOMAA PHARMAKA GMBH (DE) | 2003-02-20 | — | — | US | disclosed |
| WO-1993002051-A1 | INDOLES | PFIZER LIMITED (GB) | 1993-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036532-A1 | Use of 2-phenylene diamine derivatives for the treatment of infections | HRH2, ASPH, NQO2 | GSK3B 3157/4885BACE1 3768/4885ABCG2 2153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.