Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862475 | 0.79 | MAPT (0.43) | MAPTMAPK1GAAMEN1KMT2A | |
| SCHEMBL6862477 | 0.79 | MAPT (0.43) | MAPTMAPK1GAAMEN1KMT2A | |
| SCHEMBL11555497 | 0.74 | GAA (0.43) | MAPTL3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL11555501 | 0.74 | GAA (0.43) | MAPTL3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL6861279 | 0.73 | NPC1 (0.40) | MAPTMAPK1NPC1RAB9AGAA | |
| SCHEMBL6861280 | 0.73 | NPC1 (0.40) | MAPTMAPK1NPC1RAB9AGAA | |
| SCHEMBL6856421 | 0.72 | ALDH1A1 (0.48) | MAPTL3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL13994776 | 0.70 | ALDH1A1 (0.55) | MAPTL3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL11449505 | 0.69 | HTT (0.42) | MAPTL3MBTL1MAPK1NPC1RAB9A | |
| SCHEMBL11449504 | 0.69 | HTT (0.42) | MAPTL3MBTL1MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305297-A1 | BENZOTRIAZOLES CONTAINING ALPHA-CUMYL GROUPS SUBSTITUTED BY HETEROATOMS AND COMPOSITIONS STABILIZED THEREWITH | Ciba SC Holding AG (CH) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002012205-A1 | BENZOTRIAZOLES CONTAINING α-CUMYL GROUPS SUBSTITUTED BY HETEROATOMS AND COMPOSITIONS STABILIZED THEREWITH | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-02-14 | — | — | WO | disclosed |