Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594547 | 0.82 | CPA1 (0.47) | CPA1ALDH1A1CYP1A2EPHX1SRR | |
| SCHEMBL490895 | 0.79 | CPA1 (0.45) | CPA1ALDH1A1 | |
| SCHEMBL7054871 | 0.76 | CPA1 (0.42) | CPA1ALDH1A1CYP1A2EPHX1 | |
| SCHEMBL5659601 | 0.75 | CPA1 (0.41) | CPA1ALDH1A1 | |
| SCHEMBL5682403 | 0.73 | CPA1 (0.47) | CPA1ALDH1A1CYP1A2SRR | |
| SCHEMBL28465583 | 0.73 | CPA1 (0.47) | CPA1CYP1A2SRRNPC1TP53 | |
| SCHEMBL3208699 | 0.73 | CPA1 (0.46) | CPA1ALDH1A1CYP1A2EPHX1NPC1 | |
| SCHEMBL1588401 | 0.72 | PIN1 (0.37) | CPA1 | |
| SCHEMBL3678018 | 0.72 | TAAR1 (0.48) | CYP1A2EPHX1NPC1RAB9A | |
| SCHEMBL187342 | 0.71 | CPA1 (0.52) | CPA1ALDH1A1CYP1A2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305299-A1 | CYCLIC POLYAMINE COMPOUNDS FOR CANCER THERAPY | SLIL Biomedical Corporation (US) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002010142-A1 | CYCLIC POLYAMINE COMPOUNDS FOR CANCER THERAPY | SLIL BIOMEDICAL CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |