Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 2/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | CCKBR | P32239 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046621 | 0.78 | BBOX1 (0.31) | — | |
| SCHEMBL2772788 | 0.73 | HRH3 (0.34) | HRH3HSD11B2ALDH1A1KMT2APTPRC | |
| SCHEMBL11122150 | 0.70 | BTK (0.36) | HRH3HSD11B2GAAALDH1A1KMT2A | |
| SCHEMBL5370358 | 0.70 | HSD11B2 (0.37) | HRH3HSD11B2ALDH1A1KMT2APTPRC | |
| SCHEMBL11366947 | 0.70 | BTK (0.45) | HRH3GAAKMT2AMEN1 | |
| SCHEMBL7277999 | 0.70 | EPHX1 (0.46) | HRH3GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL23759208 | 0.69 | HRH3 (0.39) | HRH3ALDH1A1 | |
| SCHEMBL7380787 | 0.69 | EPHX1 (0.38) | HRH3HSD11B2GAAALDH1A1KMT2A | |
| SCHEMBL11373425 | 0.68 | EPHX1 (0.49) | GAAKMT2AMEN1 | |
| SCHEMBL2547400 | 0.68 | EPHX1 (0.49) | GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979816-B1 | Hydroxamic acid derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-05-02 | — | — | EP | disclosed |
| EP-0979816-A1 | Hydroxamic acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-02-16 | — | — | EP | disclosed |