⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779728 | 0.85 | — | — | |
| SCHEMBL2837146 | 0.78 | IDO1 (0.35) | — | |
| SCHEMBL17907429 | 0.77 | — | — | |
| SCHEMBL6511573 | 0.76 | IDO1 (0.33) | — | |
| SCHEMBL6512995 | 0.76 | IDO1 (0.33) | — | |
| SCHEMBL1094237 | 0.74 | ACHE (0.47) | — | |
| SCHEMBL280535 | 0.74 | ACHE (0.47) | — | |
| SCHEMBL254471 | 0.74 | ACHE (0.47) | — | |
| SCHEMBL514594 | 0.72 | MEN1 (0.44) | — | |
| SCHEMBL10200928 | 0.72 | MEN1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073454-B1 | 6-ALPHA-METHOXY-PENICILLINS, THEIR SALTS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1985-05-02 | — | — | EP | claimed |
| US-4454128-A | ANTIBIOTICS | DR. KARL THOMAE GMBH (DE) | 1984-06-12 | — | — | US | claimed |
| EP-0035161-B1 | CEPHALOSPORINS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1983-11-23 | — | — | EP | claimed |
| EP-0073454-A2 | 6-Alpha-methoxy-penicillins, their salts, process for their preparation and therapeutic agents containing these compounds | Dr. Karl Thomae GmbH (DE) | 1983-03-09 | — | — | EP | claimed |
| US-4370327-A | Cephalosporins and pharmaceutical compositions | BOEHRINGER INGELHEIM GMBH (DE) | 1983-01-25 | — | — | US | claimed |
| EP-0035161-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing these compounds | Dr. Karl Thomae GmbH (DE) | 1981-09-09 | — | — | EP | claimed |
| EP-0003814-A2 | Penicillins, their salts, process for their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1979-09-05 | — | — | EP | claimed |
| EP-0882715-B1 | NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES | KUREHA CHEMICAL IND CO LTD (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6339045-B1 | CAN BE USED IN A SMALL AMOUNT, SHOWING A GOOD SELECTIVITY BETWEEN CROP AND WEED, AND CAUSING NO PHYTOTOXICITY | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-01-15 | — | — | US | disclosed |
| EP-0882715-A1 | NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-12-09 | — | — | EP | disclosed |
| EP-0073454-B1 | 6-ALPHA-METHOXY-PENICILLINS, THEIR SALTS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1985-05-02 | — | — | EP | disclosed |
| US-4454128-A | ANTIBIOTICS | DR. KARL THOMAE GMBH (DE) | 1984-06-12 | — | — | US | disclosed |
| EP-0035161-B1 | CEPHALOSPORINS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1983-11-23 | — | — | EP | disclosed |
| EP-0073454-A2 | 6-Alpha-methoxy-penicillins, their salts, process for their preparation and therapeutic agents containing these compounds | Dr. Karl Thomae GmbH (DE) | 1983-03-09 | — | — | EP | disclosed |
| US-4370327-A | Cephalosporins and pharmaceutical compositions | BOEHRINGER INGELHEIM GMBH (DE) | 1983-01-25 | — | — | US | disclosed |
| EP-0035161-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing these compounds | Dr. Karl Thomae GmbH (DE) | 1981-09-09 | — | — | EP | disclosed |