Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | CA1 | P00915 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053572 | 1.00 | MAPT (0.61) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL3487513 | 1.00 | MAPT (0.61) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL14292320 | 1.00 | MAPT (0.61) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL4754008 | 1.00 | MAPT (0.61) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL4754009 | 1.00 | MAPT (0.61) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11790195 | 0.98 | MAPT (0.60) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL14292324 | 0.95 | MAPT (0.68) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28789732 | 0.95 | MAPT (0.68) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11475684 | 0.84 | CA1 (0.64) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL3487030 | 0.83 | MAPT (0.51) | MAPTCA1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015000543-A1 | RARE EARTH METAL-BIS(PERFLUOROALKYL)PHOSPHINATES AS LEWIS ACID CATALYSTS | MERCK PATENT GMBH (DE) | 2015-01-08 | — | — | WO | disclosed |
| EP-0811629-B1 | OPTICALLY ACTIVE BIDENTATE PHOSPHINE LIGAND/PALLADIUM COMPLEX | NISSAN CHEMICAL IND LTD (JP) | 2003-05-02 | — | — | EP | disclosed |
| US-5880301-A | CATALYSTS FOR PREPARATION OF OPTICALLY ACTIVE BETA-HYDROXYKETONES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0811629-A1 | OPTICALLY ACTIVE BIDENTATE PHOSPHINE LIGAND/PALLADIUM COMPLEX | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-12-10 | — | — | EP | disclosed |