Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | CA1 | P00915 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053572 | 1.00 | MAPT (0.61) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL14292320 | 1.00 | MAPT (0.61) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL4754008 | 1.00 | MAPT (0.61) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7055028 | 1.00 | MAPT (0.61) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL4754009 | 1.00 | MAPT (0.61) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11790195 | 0.98 | MAPT (0.60) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL14292324 | 0.95 | MAPT (0.68) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28789732 | 0.95 | MAPT (0.68) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11475684 | 0.84 | CA1 (0.64) | MAPTCA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL3487030 | 0.83 | MAPT (0.51) | MAPTCA1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627647-A | High diastereoselectivity 2- (hydroxy (phenyl) methyl) cyclohexanone derivative and preparation method thereof | 广东工业大学 | 2019-12-31 | — | — | CN | claimed |
| CN-110627647-A | High diastereoselectivity 2- (hydroxy (phenyl) methyl) cyclohexanone derivative and preparation method thereof | 广东工业大学 | 2019-12-31 | — | — | CN | disclosed |
| CN-110627647-A | High diastereoselectivity 2- (hydroxy (phenyl) methyl) cyclohexanone derivative and preparation method thereof | 广东工业大学 | 2019-12-31 | — | — | CN | disclosed |
| CN-110627647-A | High diastereoselectivity 2- (hydroxy (phenyl) methyl) cyclohexanone derivative and preparation method thereof | 广东工业大学 | 2019-12-31 | — | — | CN | disclosed |
| WO-2015000543-A1 | RARE EARTH METAL-BIS(PERFLUOROALKYL)PHOSPHINATES AS LEWIS ACID CATALYSTS | MERCK PATENT GMBH (DE) | 2015-01-08 | — | — | WO | disclosed |
| US-8399684-B2 | Sulfonamide-based organocatalysts and method for their use | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2013-03-19 | — | — | US | disclosed |
| US-20100184986-A1 | SULFONAMIDE-BASED ORGANOCATALYSTS AND METHOD FOR THEIR USE | The State of Oregon acting by and through the State Board of Higher Education on behalf of Orego | 2010-07-22 | — | — | US | disclosed |
| WO-2009039181-A2 | SULFONAMIDE-BASED ORGANOCATALYSTS AND METHOD FOR THEIR USE | STATE OF OREGON ACTING BY & THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OR. STATE UNIV. (US) | 2009-03-26 | — | — | WO | disclosed |
| WO-2008022961-A1 | N-HETEROCYCLES SUPPORTED ON POLYMERS THROUGH TRIAZOLE OR TETRAZOLE LINKERS FOR ORGANOCATALYTIC APPLICATIONS | INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) | 2008-02-28 | — | — | WO | disclosed |
| EP-1892042-A1 | Proline derivatives supported on polymers through triazole or tetrazole linkers for organocatalytic applications | Institut Catala D'Investigacio Quimica (ES) | 2008-02-27 | — | — | EP | disclosed |
| EP-0811629-B1 | OPTICALLY ACTIVE BIDENTATE PHOSPHINE LIGAND/PALLADIUM COMPLEX | NISSAN CHEMICAL IND LTD (JP) | 2003-05-02 | — | — | EP | disclosed |
| US-5880301-A | CATALYSTS FOR PREPARATION OF OPTICALLY ACTIVE BETA-HYDROXYKETONES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0811629-A1 | OPTICALLY ACTIVE BIDENTATE PHOSPHINE LIGAND/PALLADIUM COMPLEX | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-12-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184986-A1 | SULFONAMIDE-BASED ORGANOCATALYSTS AND METHOD FOR THEIR USE | ALDH7A1, SULT1A1, SULT2A1 | MAPT 3451/4885CA1 1253/4885KDM4E 3481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.