SCHEMBL7055122

SCHEMBL7055122

O=C(O[SiH3])C(Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.59
KCNN4 O15554 1/20 0.44
TSHR P16473 1/20 0.41
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
CES1 P23141 1/20 0.36
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
CHRM2 P08172 3/20 0.35
CHRM1 P11229 3/20 0.35
CHRM3 P20309 3/20 0.35
ALOX15 P16050 1/20 0.34
HDAC3 O15379 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27264055 0.81 CYP1A2 (0.61) CYP1A2KCNN4TSHRCNR1CNR2
SCHEMBL7056401 0.80 KCNN4 (0.46) CYP1A2KCNN4TSHRMAPTKMT2A
Ammonia Solution, Strong SCHEMBL28235508 0.79 CYP1A2 (0.59) CYP1A2KCNN4TSHRCNR1CNR2
SCHEMBL27449855 0.79 CYP1A2 (0.59) CYP1A2KCNN4TSHRCNR1CNR2
SCHEMBL27558804 0.79 CYP1A2 (0.59) CYP1A2KCNN4TSHRCNR1CNR2
SCHEMBL10725564 0.79 CYP1A2 (0.59) CYP1A2KCNN4TSHRCNR1CNR2
SCHEMBL27468337 0.79 CYP1A2 (0.59) CYP1A2KCNN4TSHRCNR1CNR2
SCHEMBL27720311 0.79 CYP1A2 (0.59) CYP1A2KCNN4TSHRCNR1CNR2
SCHEMBL2419456 0.79 KCNN4 (0.64) CYP1A2KCNN4TSHRCNR1CNR2
SCHEMBL27799952 0.79 CYP1A2 (0.59) CYP1A2KCNN4TSHRCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006118-B1 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond DOW CORNING ASIA LTD (JP) 2003-05-07 EP disclosed
US-6175031-B1 PLATINUM-CATALYZED HYDROSILYLATION BETWEEN SIH-SUBSTITUTED SILICON COMPOUNDS AND UNSATURATED GROUP-FUNCTIONAL ORGANIC OR ORGANOSILICON COMPOUNDS IN PRESENCE OF A (ACYLOXY)-FUNCTIONAL HYDROGENSILANE COMPOUND OR ACID AND HYDRO(ALKOXY)SILANE DOW CORNING ASIA, LTD. (JP) 2001-01-16 US disclosed
US-6111126-A Method for synthesizing organosilicon compounds that contain a functional group bonded to silicon across the Si-C bond DOW CORNING ASIA, LTD. (JP) 2000-08-29 US disclosed
EP-1006118-A2 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond Dow Corning Asia, Ltd. (JP) 2000-06-07 EP disclosed