Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 4/20 | 0.45 |
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.45 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335965 | 0.82 | FFAR1 (0.57) | FFAR1FFAR4CNR1MEP1AMEP1B | |
| SCHEMBL3491515 | 0.81 | FFAR1 (0.72) | FFAR1FFAR4CNR1LMNA | |
| SCHEMBL6364918 | 0.80 | FFAR1 (0.55) | FFAR1FFAR4CNR1MEP1AMEP1B | |
| SCHEMBL2411845 | 0.80 | FFAR1 (0.55) | FFAR1FFAR4CNR1MEP1AMEP1B | |
| SCHEMBL934610 | 0.80 | FFAR1 (0.55) | FFAR1FFAR4CNR1MEP1AMEP1B | |
| Trifluoroacetic Acid SCHEMBL3750230 | 0.79 | FFAR1 (0.49) | FFAR1FFAR4CNR1MEP1AMEP1B | |
| SCHEMBL10431231 | 0.78 | CES1 (0.50) | CES1FAAHPLA2G4A | |
| SCHEMBL27322168 | 0.77 | FFAR1 (0.52) | FFAR1FFAR4FAAHCNR1MEP1A | |
| SCHEMBL2154019 | 0.76 | GLA (0.53) | FFAR1FFAR4CNR1MEP1AMEP1B | |
| SCHEMBL17546408 | 0.76 | FFAR1 (0.51) | FFAR1FFAR4CNR1MEP1AMEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307429-A1 | PROCESS FOR ASYMMETRIC SYNTHESIS OF SUBSTITUTED 1,4-DIHYDROPYRIDINES | AstraZeneca AB (SE) | 2003-05-07 | — | — | EP | disclosed |
| EP-1307420-A1 | PROCESS FOR SYNTHESIS OF $g(a),$g(b)-UNSATURATED KETONES | AstraZeneca AB (SE) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002010134-A1 | PROCESS FOR ASYMMETRIC SYNTHESIS OF SUBSTITUTED 1,4-DIHYDROPYRIDINES | ASTRAZENECA AB (SE) | 2002-02-07 | — | — | WO | disclosed |
| WO-2002010103-A1 | PROCESS FOR SYNTHESIS OF α,β-UNSATURATED KETONES | ASTRAZENECA AB (SE) | 2002-02-07 | — | — | WO | disclosed |