Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247244 | 0.82 | TSHR (0.64) | TSHRALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL623935 | 0.80 | MGAM (0.41) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL5474403 | 0.79 | GAA (0.40) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL1898254 | 0.77 | MGAM (0.52) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL6292361 | 0.77 | TSHR (0.41) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL30059382 | 0.77 | TSHR (0.50) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL7678018 | 0.77 | TSHR (0.68) | TSHRGAAALDH1A1PPARGNCOA2 | |
| SCHEMBL472554 | 0.77 | TSHR (0.50) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL5143366 | 0.76 | GAA (0.38) | TSHRGAAMGAMSIMGAM2 | |
| SCHEMBL27551575 | 0.75 | TSHR (0.48) | TSHRGAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1034229-B1 | COATING COMPOSITIONS CONTAINING A HIGHLY FLUORINATED POLYMERIC ADDITIVE | DU PONT (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-1034229-A1 | COATING COMPOSITIONS CONTAINING A HIGHLY FLUORINATED POLYMERIC ADDITIVE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-09-13 | — | — | EP | disclosed |
| US-5948851-A | HYDROXY-CONTAINING ACRYLIC COPOLYMER, FLUORINATED ACRYLIC COPOLYMER, CROSSLINKING AGENT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-09-07 | — | — | US | disclosed |
| WO-1999027025-A1 | COATING COMPOSITIONS CONTAINING A HIGHLY FLUORINATED POLYMERIC ADDITIVE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |