SCHEMBL70554

SCHEMBL70554

Nc1ccccc1C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
POLB P06746 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
CYP3A4 P08684 1/20 0.47
ALOX15 P16050 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
IDO1 P14902 2/20 0.45
CUL4A Q13619 1/20 0.43
HTR2C P28335 3/20 0.41
HTR2B P41595 1/20 0.41
TSHR P16473 2/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41
BACE1 P56817 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29882203 1.00 ALDH1A1 (0.48) ALDH1A1L3MBTL1POLBTDP1CYP3A4
SCHEMBL8994564 1.00 ALDH1A1 (0.48) ALDH1A1L3MBTL1POLBTDP1CYP3A4
Hydrochloric Acid SCHEMBL4371044 0.97 TDP1 (0.52) ALDH1A1L3MBTL1POLBTDP1CYP3A4
Water SCHEMBL6244814 0.97 POLB (0.46) ALDH1A1L3MBTL1POLBTDP1CYP3A4
Fluoride SCHEMBL7897532 0.97 POLB (0.46) ALDH1A1L3MBTL1POLBTDP1CYP3A4
Hydrochloric Acid SCHEMBL1768867 0.97 TDP1 (0.52) ALDH1A1L3MBTL1POLBTDP1CYP3A4
Ammonia Solution, Strong SCHEMBL8056717 0.97 POLB (0.46) ALDH1A1L3MBTL1POLBTDP1CYP3A4
Hydrogen Sulfide SCHEMBL11147516 0.97 POLB (0.46) ALDH1A1L3MBTL1POLBTDP1CYP3A4
Aniline SCHEMBL22169163 0.91 TSHR (0.50) ALDH1A1L3MBTL1POLBTDP1CYP3A4
Boric Acid SCHEMBL28518791 0.91 TDP1 (0.42) ALDH1A1L3MBTL1POLBTDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3787 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094389-A Perovskite material, perovskite layer, preparation method of perovskite layer, perovskite solar cell and photovoltaic module 2026-05-26 CN claimed
CN-122036476-A Preparation method of 4- (4-chlorophenoxy) -2-trifluoromethyl acetophenone 江西天宇化工有限公司 2026-05-15 CN claimed
US-12528777-B2 Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2026-01-20 US claimed
WO-2025125665-A1 FURTHER SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2025-06-19 WO claimed
CN-114420852-B Preparation method of pure-phase RP perovskite film 河北工业大学 2025-05-27 CN claimed
CN-119869420-A Trifluoromethyl aniline cauldron raffinate resourceful utilization equipment 安徽鑫泰新材料有限公司 2025-04-25 CN claimed
CN-114824092-B Solar cell based on quasi-two-dimensional perovskite and preparation method thereof 北京炎和科技有限公司 2025-04-18 CN claimed
CN-119798108-A Preparation method of inner-ring profenofos and intermediate thereof in micro-channel 福州大学 2025-04-11 CN claimed
CN-119684069-A Method for preparing beta-trichloromethyl butyl ester or amide 中国科学院大连化学物理研究所 2025-03-25 CN claimed
WO-2025044027-A1 PREPARATION METHOD FOR HIGH-CONTENT 2-TRIFLUOROMETHYL-4-HEPTAFLUOROISOPROPYL ANILINE 浙江宇龙药业有限公司 2025-03-06 WO claimed
EP-0039810-A1 Process for the preparation of 2-trifluoromethyl aniline BAYER AG (DE) 1981-11-18 EP claimed
EP-0038465-A1 Process for the preparation of 2-trifluoromethyl aniline HOECHST AKTIENGESELLSCHAFT (DE) 1981-10-28 EP claimed
EP-0026894-A1 Process for the preparation of erythro-alpha-2-piperidyl-2,8-bis (trifluoromethyl)-4-quinoline methanol BASF Aktiengesellschaft (DE) 1981-04-15 EP claimed
EP-0003766-A1 N-(omega-chloroalcanoyl)-N'-trifluoromethylphenyl-urea, preparation thereof and use thereof as plant-protecting agents BAYER AG (DE) 1979-09-05 EP claimed
US-4076537-A Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US claimed
US-4008278-A FROM AN AMINO-BENZOTRIFLUORIDE AND A HALOGEN SOURCE OLIN CORPORATION (US) 1977-02-15 US claimed
US-3983048-A Composition for accelerating oxygen removal comprised of a mixture of aqueous hydrazine and an aryl amine compound OLIN CORPORATION (US) 1976-09-28 US claimed
US-3978049-A Process for the preparation of hydrazine compounds PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-08-31 US claimed
US-3972878-A Method for preparing azines and hydrazones PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-08-03 US claimed
US-3943132-A Process for the preparation of hydrazones PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-09 US claimed