SCHEMBL7055672

SCHEMBL7055672

CCCC[N+]1(CCCC)CC1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.35
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4903180 1.00 TSHR (0.38) TSHRLMNATHRBALDH1A1TDP1
Bromide SCHEMBL17055040 0.97 TSHR (0.35) TSHRLMNATHRBALDH1A1
SCHEMBL14752324 0.94 TSHR (0.33) TSHRLMNATHRB
SCHEMBL10721819 0.88 TSHR (0.47) TSHRLMNATHRBALDH1A1
SCHEMBL830522 0.88 TSHR (0.33) TSHRLMNATHRB
SCHEMBL11873435 0.88 TSHR (0.47) TSHRLMNATHRBALDH1A1
SCHEMBL7522015 0.88 TSHR (0.47) TSHRLMNATHRBALDH1A1
Hydrochloric Acid SCHEMBL2469834 0.85 TSHR (0.44) TSHRLMNATHRBALDH1A1
SCHEMBL9936130 0.85 TSHR (0.32) TSHRLMNATHRB
SCHEMBL829066 0.85 CYP1A2 (0.33) TSHRLMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6576738-B2 Catalyst removal from a polymerization reaction mixture by adding a polar liquid and centrifuging, and isolating the poly(arylene ether) without the addition of a low viscosity polymer other than poly(arylene ether) GENERAL ELECTRIC COMPANY 2003-06-10 US disclosed
EP-1303555-A2 POLY(ARYLENE ETHER) AND PROCESS FOR MAKING THE SAME GENERAL ELECTRIC COMPANY (US) 2003-04-23 EP disclosed
US-20020115822-A1 Poly (arylene ether) and process for making the same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2002-08-22 US disclosed
US-6407202-B1 MIXING WITH CATALYST, CENTRIFUGING, HEATING, FLASHING GENERAL ELECTRIC COMPANY 2002-06-18 US disclosed
WO-2002006376-A2 POLY(ARYLENE ETHER) AND PROCESS FOR MAKING THE SAME GENERAL ELECTRIC COMPANY (US) 2002-01-24 WO disclosed