Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2469834

CCCCCCCCCC[N+]1(CCCCCCCCCC)CC1.[Cl-]

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.44
GNAI3 P08754 1/20 0.41
GNAO1 P09471 1/20 0.41
GNAI1 P63096 1/20 0.41
DNM1 Q05193 5/20 0.36
ALDH1A1 P00352 2/20 0.35
LMNA P02545 2/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SLC22A1 O15245 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11873435 0.97 TSHR (0.47) TSHRTHRBGNAI3GNAO1GNAI1
SCHEMBL10721819 0.97 TSHR (0.47) TSHRTHRBGNAI3GNAO1GNAI1
SCHEMBL7522015 0.97 TSHR (0.47) TSHRTHRBGNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL30212644 0.87 TSHR (0.38) TSHRTHRBGNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL30212781 0.87 TSHR (0.38) TSHRTHRBGNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL30212919 0.87 TSHR (0.38) TSHRTHRBGNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL30212851 0.87 TSHR (0.38) TSHRTHRBGNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL30212634 0.87 TSHR (0.38) TSHRTHRBGNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL16666207 0.87 TSHR (0.38) TSHRTHRBGNAI3GNAO1GNAI1
Hydrochloric Acid SCHEMBL30212794 0.87 TSHR (0.38) TSHRTHRBGNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1893802-B1 SILOXANE-CONTAINING FORMULATION FOR REDUCING CREASE FORMATION HENKEL AG & CO KGAA (DE) 2011-10-05 EP disclosed
EP-1893802-A1 SILOXANE-CONTAINING FORMULATION FOR REDUCING CREASE FORMATION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-03-05 EP disclosed
EP-1876895-A2 HALOMETHYLENE ALKANONES AND FURANONES FOR USE AS BIOFILM BLOCKING SUBSTANCES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-01-16 EP disclosed
WO-2006136382-A1 SILOXANE-CONTAINING FORMULATION FOR REDUCING CREASE FORMATION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-12-28 WO disclosed
WO-2006117113-A2 HALOMETHYLENE ALKANONES AND FURANONES FOR USE AS BIOFILM BLOCKING SUBSTANCES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-11-09 WO disclosed
WO-2005017083-A1 CLEANING PRODUCT FOR GENTLY TREATING ACID-SENSITIVE CARBONATE CONTAINING SURFACES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-02-24 WO disclosed