Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061675 | 0.92 | KDM4E (0.37) | KDM4EL3MBTL1TDP1MAPK1HSD17B10 | |
| SCHEMBL7057483 | 0.89 | KDM4E (0.39) | KDM4EL3MBTL1TDP1MAPK1HSD17B10 | |
| SCHEMBL7060393 | 0.88 | MAPK1 (0.39) | KDM4EL3MBTL1TDP1MAPK1HSD17B10 | |
| SCHEMBL7061260 | 0.81 | KDM4E (0.40) | KDM4EL3MBTL1TDP1MAPK1HSD17B10 | |
| SCHEMBL7058670 | 0.80 | MAPK1 (0.36) | KDM4EL3MBTL1TDP1MAPK1HSD17B10 | |
| SCHEMBL7057726 | 0.80 | MAPK1 (0.36) | KDM4EL3MBTL1TDP1MAPK1HSD17B10 | |
| SCHEMBL6499213 | 0.79 | HSD17B10 (0.44) | KDM4EL3MBTL1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL7056212 | 0.78 | KDM4E (0.41) | KDM4EL3MBTL1TDP1MAPK1HSD17B10 | |
| SCHEMBL7057147 | 0.77 | KDM4E (0.39) | KDM4EL3MBTL1TDP1MAPK1HSD17B10 | |
| SCHEMBL6492344 | 0.77 | HSD17B10 (0.42) | KDM4EL3MBTL1TDP1MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003035618-A2 | MODULATORS OF PHOSPHOINOSITIDE 3-KINASE | ICONIX PHARMACEUTICALS, INC. (US) | 2003-05-01 | — | — | WO | disclosed |