Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061260 | 0.89 | KDM4E (0.40) | KDM4ELMNAHSD17B10MAPK1USP2 | |
| SCHEMBL7055136 | 0.86 | KDM4E (0.38) | KDM4ELMNAHSD17B10MAPK1USP2 | |
| SCHEMBL6492344 | 0.82 | HSD17B10 (0.42) | KDM4ELMNAHSD17B10MAPK1USP2 | |
| SCHEMBL6499160 | 0.82 | HSD17B10 (0.44) | KDM4ELMNAHSD17B10MAPK1USP2 | |
| SCHEMBL7056212 | 0.81 | KDM4E (0.41) | KDM4ELMNAHSD17B10MAPK1USP2 | |
| SCHEMBL7057483 | 0.80 | KDM4E (0.39) | KDM4ELMNAHSD17B10MAPK1USP2 | |
| SCHEMBL7055635 | 0.78 | KDM4E (0.39) | KDM4ELMNAHSD17B10MAPK1USP2 | |
| SCHEMBL6489335 | 0.78 | HSD17B10 (0.46) | KDM4ELMNAHSD17B10MAPK1USP2 | |
| SCHEMBL7055682 | 0.77 | KDM4E (0.39) | KDM4ELMNAHSD17B10MAPK1USP2 | |
| SCHEMBL7059144 | 0.76 | ELANE (0.44) | KDM4ELMNAHSD17B10MAPK1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003035618-A2 | MODULATORS OF PHOSPHOINOSITIDE 3-KINASE | ICONIX PHARMACEUTICALS, INC. (US) | 2003-05-01 | — | — | WO | disclosed |