Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056155 | 0.86 | F2 (0.48) | F2PLAUKLKB1ELANEL3MBTL1 | |
| SCHEMBL24937400 | 0.86 | L3MBTL1 (0.56) | F2PLAUKLKB1ELANEL3MBTL1 | |
| SCHEMBL31460083 | 0.84 | F2 (0.47) | F2PLAUKLKB1ELANEL3MBTL1 | |
| SCHEMBL20660787 | 0.83 | F2 (0.46) | F2PLAUKLKB1ELANEL3MBTL1 | |
| SCHEMBL30829495 | 0.83 | F2 (0.46) | F2PLAUKLKB1ELANEL3MBTL1 | |
| SCHEMBL24875516 | 0.81 | F2 (0.44) | F2PLAUKLKB1ELANEL3MBTL1 | |
| SCHEMBL20156357 | 0.80 | MAPK1 (0.44) | F2PLAUKLKB1ELANEL3MBTL1 | |
| SCHEMBL21626155 | 0.80 | F2 (0.43) | F2PLAUKLKB1ELANEL3MBTL1 | |
| SCHEMBL796641 | 0.80 | F2 (0.43) | F2PLAUKLKB1ELANEL3MBTL1 | |
| SCHEMBL15898282 | 0.80 | F2 (0.43) | F2PLAUKLKB1ELANEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | claimed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |