Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 16/20 | 0.59 |
| ▸ | CA1 | P00915 | 16/20 | 0.59 |
| ▸ | CA2 | P00918 | 16/20 | 0.59 |
| ▸ | CA9 | Q16790 | 15/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 12/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PRKCA | P17252 | 1/20 | 0.53 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051012 | 0.94 | CA12 (0.65) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL16492293 | 0.84 | CA12 (0.55) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL3393349 | 0.84 | LMNA (0.73) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL20202226 | 0.84 | LMNA (0.73) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL20202245 | 0.84 | LMNA (0.58) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL17527987 | 0.84 | LMNA (0.73) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL7152557 | 0.84 | LMNA (0.73) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL20202239 | 0.84 | LMNA (0.73) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL7152558 | 0.84 | LMNA (0.73) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL20202228 | 0.84 | LMNA (0.73) | TSHRCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003018598-A2 | MONOSACCHARIDE DERIVATIVES | UNIVERSITY COLLEGE DUBLIN (IE) | 2003-03-06 | — | — | WO | disclosed |