Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28697 | 0.95 | TDP1 (0.79) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL8558572 | 0.89 | TDP1 (0.76) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| Benzoic Acid SCHEMBL2494208 | 0.89 | TSHR (0.89) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL28465057 | 0.88 | ALDH1A1 (0.69) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL27961460 | 0.88 | TSHR (0.69) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| Isophthalic Acid SCHEMBL30938816 | 0.87 | HSD17B10 (0.57) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL2043890 | 0.87 | HSD17B10 (0.57) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL29978543 | 0.87 | HSD17B10 (0.57) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL27694994 | 0.85 | TDP1 (0.65) | TSHRTDP1ALDH1A1HSD17B10LMNA | |
| SCHEMBL8108990 | 0.85 | TSHR (0.62) | TSHRTDP1ALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101205430-B | Ink-jet recording ink | SEIKO EPSON CORP. (JP) | 2012-02-15 | — | — | CN | disclosed |
| CN-101205431-A | Ink-jet recording ink | SEIKO EPSON CORP (JP) | 2008-06-25 | — | — | CN | disclosed |
| CN-101205430-A | Ink-jet recording ink | SEIKO EPSON CORP (JP) | 2008-06-25 | — | — | CN | disclosed |
| EP-0863167-B1 | Process for producing a copolymer of methyl methacrylate and styrene | MITSUBISHI GAS CHEMICAL CO (JP) | 2003-05-02 | — | — | EP | disclosed |
| US-5980790-A | POLYMERIZING STYRENE AND METHYL METHACRYLATE IN HOMOGENEOUS SOLUTION COMPRISING METHYL METHACRYLATE, STYRENE, AND ANTIOXIDANT BY CONTINUOUSLY SUPPLYING INTO REACTOR AND CONTINUOUSLY REMOVING AND EXTRUDING PRODUCT | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0747399-B1 | Adhesive tape for electronic parts and liquid adhesive | TOMOEGAWA PAPER CO LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| EP-0863167-A1 | Process for producing a copolymer | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1998-09-09 | — | — | EP | disclosed |
| EP-0649892-B1 | Adhesive tape for electronic parts and liquid adhesive | TOMOEGAWA PAPER CO LTD (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0649893-B1 | Adhesive tape for electronic parts and liquid adhesive | TOMOEGAWA PAPER CO LTD (JP) | 1998-05-20 | — | — | EP | disclosed |
| EP-0651040-B1 | Liquid adhesive for electronic parts and process for forming insulating adhesive layer using the same | TOMOEGAWA PAPER CO LTD (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5609956-A | (PIPERAZINYLETHYLAMINO)CARBONYL-CONTAINING ACRYLONITRILE-BUTADIENE COPOLYMER, MALEIMIDE COMPOUND | TOMOEGAWA PAPER CO., LTD. (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0747399-A2 | Adhesive tape for electronic parts and liquid adhesive | TOMOEGAWA PAPER CO. LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |
| US-5512628-A | COMBINING A PIPERAZINYLETHYLAMINOCARBONYL-CONTAINING BUTADIENE-ACRYLONITRILE COPOLYMER WITH A MALEIMIDE CONTAINING COMPOUND IN AN ORGANIC SOLVENT; CURABLE | TOMOEGAWA PAPER CO., LTD. (JP) | 1996-04-30 | — | — | US | disclosed |
| US-5510189-A | COMPRISING A PIPERAZINYLETHYLAMINOCARBONYL-CONTAINING BUTADIENE-ACRYLONITRILE COPOLYMER AND A MALEIMIDE COMPOUND; ADHERED AND CURED AT LOW TEMPERATURE; HEAT RESISTANCE | TOMOEGAWA PAPER CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| US-5500294-A | MODIFIED ACRYLONITRILE-BUTADIENE COPOLYMER | TOMOEGAWA PAPER CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| US-5494757-A | BLEND OF A PIPERAZINYLETHYLAMIDOCARBONYL-CONTAINING BUTADIENE-ACRYLONITRILE TERPOLYMER AND A MALEIMIDE RESIN | TOMOEGAWA PAPER CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| US-5446080-A | Piperazinylethylaminocarbonyl containing acrylonitrile-butadiene copolymer and bismaleimide compound | TOMOEGAWA PAPER CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0651040-A1 | Liquid adhesive for electronic parts and process for forming insulating adhesive layer using the same | TOMOEGAWA PAPER CO. LTD. (JP) | 1995-05-03 | — | — | EP | disclosed |
| EP-0649892-A1 | Adhesive tape for electronic parts and liquid adhesive | TOMOEGAWA PAPER CO. LTD. (JP) | 1995-04-26 | — | — | EP | disclosed |
| EP-0649893-A1 | Adhesive tape for electronic parts and liquid adhesive | TOMOEGAWA PAPER CO. LTD. (JP) | 1995-04-26 | — | — | EP | disclosed |