SCHEMBL7056764

SCHEMBL7056764

CN(C)c1cccc(C(=O)c2cccc(N(C)C)c2)c1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.59
RAB9A P51151 3/20 0.59
NPC1 O15118 2/20 0.59
ALDH1A1 P00352 4/20 0.56
MAPT P10636 3/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
KMT2A Q03164 1/20 0.56
LMNA P02545 2/20 0.54
POLB P06746 1/20 0.54
TSHR P16473 1/20 0.54
KDM4E B2RXH2 5/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
HSD17B10 Q99714 2/20 0.53
GFER P55789 1/20 0.53
ATM Q13315 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
ALOX15 P16050 1/20 0.49
USP2 O75604 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL610059 0.94 HPGD (0.69) HPGDRAB9ANPC1ALDH1A1MAPT
SCHEMBL1072468 0.92 HPGD (0.72) HPGDRAB9ANPC1ALDH1A1MAPT
SCHEMBL6654680 0.88 HPGD (0.56) HPGDRAB9ANPC1ALDH1A1MAPT
SCHEMBL29625195 0.85 KMT2A (0.58) HPGDRAB9ANPC1ALDH1A1MAPT
SCHEMBL334924 0.85 KDM4E (0.56) HPGDRAB9ANPC1ALDH1A1MAPT
SCHEMBL222176 0.85 KMT2A (0.58) HPGDRAB9ANPC1ALDH1A1MAPT
SCHEMBL28398838 0.85 MAPK14 (0.56) HPGDRAB9ANPC1ALDH1A1MAPT
SCHEMBL29587672 0.85 MAPK14 (0.56) HPGDRAB9ANPC1ALDH1A1MAPT
SCHEMBL11740612 0.85 RAB9A (0.53) HPGDRAB9ANPC1ALDH1A1MAPT
SCHEMBL10943761 0.83 HPGD (0.51) HPGDRAB9ANPC1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0709438-B1 Active energy ray-curable composition recording medium and image-forming method employing the same CANON KK (JP) 2003-04-23 EP disclosed
US-6143363-A INK RECEIVER LAYER FOR PRINTING OF VARIOUS PRODUCTS POOR IN ABSORPTION OF WATER-BASED INK, CANON KABUSHIKI KAISHA (JP) 2000-11-07 US disclosed
US-5861194-A POLYAMINES FROM EPICHLOROHYDRIN AND AMINES AND ADDITION POLYMERS CANON KABUSHIKI KAISHA (JP) 1999-01-19 US disclosed
US-5798397-A PHOTOCURABLE ACRYLIC OR METHACRYLIC ESTERS OR AMIDES CONTAINING TETRAALKYL AMMONIUM GROUP; CURING CANON KABUSHIKI KAISHA (JP) 1998-08-25 US disclosed
EP-0738608-A2 Curable compositions and their use for the formation of a printing material CANON KABUSHIKI KAISHA (JP) 1996-10-23 EP disclosed
EP-0709438-A1 Active energy ray-curable composition recording medium and image-forming method employing the same CANON KABUSHIKI KAISHA (JP) 1996-05-01 EP disclosed