SCHEMBL7056977

SCHEMBL7056977

C[Si](Cl)(C1c2ccccc2-c2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.43
SLC22A2 O15244 1/20 0.38
SLC22A3 O75751 1/20 0.38
HTR2A P28223 1/20 0.38
POLB P06746 2/20 0.36
ACHE P22303 2/20 0.35
CHRM2 P08172 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
CHRM1 P11229 1/20 0.35
DRD1 P21728 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
ADRA1A P35348 1/20 0.35
OPRM1 P35372 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7048563 0.86 GPR3 (0.43) GPR3SLC22A2SLC22A3HTR2APOLB
SCHEMBL2480013 0.86 GPR3 (0.43) GPR3SLC22A2SLC22A3HTR2APOLB
SCHEMBL29596197 0.86 GPR3 (0.43) GPR3SLC22A2SLC22A3HTR2APOLB
SCHEMBL30390148 0.80 GPR3 (0.46) GPR3SLC22A2SLC22A3HTR2APOLB
SCHEMBL2546783 0.80 GPR3 (0.41) GPR3SLC22A2SLC22A3HTR2APOLB
SCHEMBL23211689 0.80 GPR3 (0.41) GPR3SLC22A2SLC22A3HTR2APOLB
SCHEMBL5981387 0.80 GPR3 (0.46) GPR3SLC22A2SLC22A3HTR2APOLB
SCHEMBL5175634 0.80 GPR3 (0.46) GPR3SLC22A2SLC22A3HTR2APOLB
SCHEMBL6671925 0.80 GPR3 (0.46) GPR3SLC22A2SLC22A3HTR2APOLB
SCHEMBL8970979 0.79 GPR3 (0.38) GPR3SLC22A2SLC22A3HTR2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304319-A2 Metallocenes and processes therefor and therewith Phillips Petroleum Company (US) 2003-04-23 EP disclosed
EP-0628566-B1 Metallocenes and processes therefor and therewith PHILLIPS PETROLEUM CO (US) 2003-03-26 EP disclosed
US-5616752-A CYCLOPENTADIENYL-TYPE SILANE-CONTAINING POLYMERIZATION CATALYSTS PHILLIPS PETROLEUM COMPANY (US) 1997-04-01 US disclosed
US-5565592-A SUPPORTED POLYMERIZATION CATALYSTS FOR OLEFINS COMPRISING ZIRCONIUM OR HAFNIUM AND AN UNSATURATED SILANE ATTACHED TO FLUORENE RINGS PHILLIPS PETROLEUM COMPANY (US) 1996-10-15 US disclosed
US-5492974-A Process for preparing polymer bound metallocenes PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492973-A Polymer bound ligands PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492978-A Process for preparing catalyst system PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492985-A Polymerization processes PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
US-5492975-A Polymer bound metallocenes PHILLIPS PETROLEUM COMPANY (US) 1996-02-20 US disclosed
EP-0690076-A1 Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1996-01-03 EP disclosed
US-5473020-A Polymer bound ligands, polymer bound metallocenes, catalyst systems, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-12-05 US disclosed
US-5466766-A Metallocenes and processes therefor and therewith PHILLIPS PETROLEUM COMPANY (US) 1995-11-14 US disclosed
US-5399636-A Bound to inorganic support, olefin polymerization catalysts PHILLIPS PETROLEUM COMPANY (US) 1995-03-21 US disclosed
EP-0628566-A1 Metallocenes and processes therefor and therewith PHILLIPS PETROLEUM COMPANY (US) 1994-12-14 EP disclosed