Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.45 |
| ▸ | PGK1 | P00558 | 1/20 | 0.44 |
| ▸ | PGK2 | P07205 | 1/20 | 0.44 |
| ▸ | PGD | P52209 | 3/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.39 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.39 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL27990255 | 0.82 | PGK1 (0.56) | PGK1PGK2PGDLPAR1LPAR5 | |
| Butyric Acid SCHEMBL23069514 | 0.82 | LPAR1 (0.50) | PGK1PGK2PGDLPAR1LPAR5 | |
| SCHEMBL7341 | 0.80 | PGK1 (0.52) | PGK1PGK2PGDLPAR1LPAR5 | |
| SCHEMBL7340 | 0.80 | PGK1 (0.52) | PGK1PGK2PGDLPAR1LPAR5 | |
| SCHEMBL14278848 | 0.80 | PGK1 (0.52) | PGK1PGK2PGDLPAR1LPAR5 | |
| SCHEMBL6655023 | 0.80 | PGK1 (0.52) | PGK1PGK2PGDLPAR1LPAR5 | |
| SCHEMBL14278847 | 0.80 | PGK1 (0.52) | PGK1PGK2PGDLPAR1LPAR5 | |
| SCHEMBL213379 | 0.80 | PGK1 (0.52) | PGK1PGK2PGDLPAR1LPAR5 | |
| Glycine SCHEMBL7202269 | 0.80 | PGK1 (0.50) | OR51E2PGK1PGK2PGDLPAR1 | |
| Selenium SCHEMBL7630839 | 0.78 | PGK1 (0.50) | PGK1PGK2PGDLPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841929-B1 | QUINOLONES AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LTD (GB) | 2003-05-07 | — | — | EP | disclosed |
| EP-1257527-A1 | (2S)-AMINOINDAN DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001062712-A1 | (2S)-AMINOINDAN DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2001-08-30 | — | — | WO | disclosed |
| EP-0841927-A1 | QUINOLONES AND THEIR THERAPEUTIC USE | Chiroscience Limited (GB) | 1998-05-20 | — | — | EP | disclosed |
| EP-0841929-A1 | QUINOLONES AND THEIR THERAPEUTIC USE | Chiroscience Limited (GB) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997004779-A1 | QUINOLONES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1997-02-13 | — | — | WO | disclosed |
| WO-1997004775-A1 | QUINOLONES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1997-02-13 | — | — | WO | disclosed |
| WO-1996036595-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |