Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.61 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.61 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.61 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.61 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19696489 | 0.91 | ALOX15 (0.72) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL9111747 | 0.89 | ALOX15 (0.72) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL9111746 | 0.89 | ALOX15 (0.72) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL9109507 | 0.89 | ALOX15 (0.72) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL9109503 | 0.89 | ALOX15 (0.72) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL6536466 | 0.86 | ALOX15 (0.79) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL3952646 | 0.86 | ALOX15 (0.79) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL3952647 | 0.86 | ALOX15 (0.79) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL460212 | 0.86 | ALOX15 (1.00) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL12417301 | 0.86 | ALOX15 (1.00) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627675-B1 | Binder which is a salt of an amine containing at least one aliphatic hydrocarbon group having 8 to 25 carbon atoms and an addition copolymer of an olefinically unsaturated sulphonic acid, acid sulphate ester, phosphonic acid or acid phosphate | INTERNATIONAL COATINGS LIMITED (GB) | 2003-09-30 | — | — | US | disclosed |
| EP-1042414-B1 | ANTIFOULING COATINGS | INT COATINGS LTD (GB) | 2003-05-02 | — | — | EP | disclosed |
| EP-1042414-A1 | ANTIFOULING COATINGS | International Coatings Limited (GB) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999037723-A1 | ANTIFOULING COATINGS | INTERNATIONAL COATINGS LIMITED (GB) | 1999-07-29 | — | — | WO | disclosed |
| WO-1996003465-A1 | ANTIFOULING COATING COMPOSITIONS | COURTAULDS COATINGS (HOLDINGS) LIMITED (GB) | 1996-02-08 | — | — | WO | disclosed |