SCHEMBL7057349

SCHEMBL7057349

CCCCCOc1ccc(-c2ccc(-c3ccc(CCC[C@@H](C)CC)cc3)cc2F)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RARB P10826 7/20 0.47
RARA P10276 2/20 0.44
MEN1 O00255 1/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPK1 P28482 1/20 0.44
CASP1 P29466 1/20 0.44
KMT2A Q03164 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
SLCO1B3 Q9NPD5 1/20 0.44
SLCO1B1 Q9Y6L6 1/20 0.44
S1PR1 P21453 3/20 0.43
S1PR3 Q99500 2/20 0.43
RARG P13631 1/20 0.42
PLA2G4A P47712 1/20 0.40
PTPN11 Q06124 2/20 0.40
FDFT1 P37268 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9514992 1.00 RARB (0.47) RARBRARAMEN1USP2ALDH1A1
SCHEMBL9513738 0.99 RARB (0.49) RARBRARAMEN1USP2ALDH1A1
SCHEMBL9225615 0.96 RARB (0.47) RARBRARAMEN1USP2ALDH1A1
SCHEMBL9229613 0.95 RARB (0.49) RARBRARAMEN1USP2ALDH1A1
SCHEMBL10336291 0.94 S1PR1 (0.48) RARBRARAMEN1USP2ALDH1A1
SCHEMBL10336144 0.94 RARB (0.50) RARBRARAMEN1USP2ALDH1A1
SCHEMBL9230366 0.91 RARB (0.45) RARBRARAALDH1A1CYP3A4S1PR1
SCHEMBL9224177 0.91 RARB (0.45) RARBRARAALDH1A1CYP3A4S1PR1
SCHEMBL9513744 0.87 RARB (0.60) RARBRARAMEN1USP2ALDH1A1
SCHEMBL9225589 0.87 RARB (0.49) RARBRARAMEN1USP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1086194-B1 MONOSTABLE FERROELECTRIC ACTIVE MATRIX DISPLAY AVENTIS RES & TECH GMBH & CO (DE) 2003-05-21 EP disclosed
EP-1086194-A1 MONOSTABLE FERROELECTRIC ACTIVE MATRIX DISPLAY Aventis Research & Technologies GmbH & Co. KG. (DE) 2001-03-28 EP disclosed
WO-1999064538-A1 MONOSTABLE FERROELECTRIC ACTIVE MATRIX DISPLAY AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-12-16 WO disclosed