Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 2/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514992 | 0.99 | RARB (0.47) | RARBMEN1USP2ALDH1A1LMNA | |
| SCHEMBL7057349 | 0.99 | RARB (0.47) | RARBMEN1USP2ALDH1A1LMNA | |
| SCHEMBL9229613 | 0.96 | RARB (0.49) | RARBMEN1USP2ALDH1A1LMNA | |
| SCHEMBL9225615 | 0.95 | RARB (0.47) | RARBMEN1USP2ALDH1A1LMNA | |
| SCHEMBL10336144 | 0.95 | RARB (0.50) | RARBMEN1USP2ALDH1A1LMNA | |
| SCHEMBL10336291 | 0.94 | S1PR1 (0.48) | RARBMEN1USP2ALDH1A1LMNA | |
| SCHEMBL9224177 | 0.92 | RARB (0.45) | RARBALDH1A1CYP3A4RARAS1PR1 | |
| SCHEMBL9230366 | 0.92 | RARB (0.45) | RARBALDH1A1CYP3A4RARAS1PR1 | |
| SCHEMBL9513744 | 0.89 | RARB (0.60) | RARBMEN1USP2ALDH1A1LMNA | |
| SCHEMBL10527704 | 0.88 | RARB (0.46) | RARBMEN1USP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391986-B1 | DISPLAY ELEMENT BASED ON THE ELECTROCLINIC EFFECT | MERCK PATENT GMBH (DE) | 1993-12-08 | — | — | EP | disclosed |
| EP-0357702-B1 | FLUORINATED OLIGOPHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-08-12 | — | — | EP | disclosed |
| US-5116527-A | Liquid crystal mixture of two chiral components and one non-chiral componene | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-05-26 | — | — | US | disclosed |
| EP-0357702-A1 | FLUORINATED OLIGOPHENYL DERIVATIVES. | MERCK PATENT GMBH (DE) | 1990-03-14 | — | — | EP | disclosed |
| WO-1989006678-A1 | FLUORINATED OLIGOPHENYL DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-07-27 | — | — | WO | disclosed |