SCHEMBL705736

SCHEMBL705736

NNC(=O)c1cc2ccc3cccc4ccc(c1C(=O)NN)c2c34

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.47
KMT2A Q03164 5/20 0.47
GAA P10253 5/20 0.47
MEN1 O00255 4/20 0.47
TDP1 Q9NUW8 2/20 0.47
MITF O75030 1/20 0.47
NCOA1 Q15788 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47
MAOB P27338 1/20 0.46
ALDH1A1 P00352 9/20 0.43
KDM4E B2RXH2 6/20 0.43
HPGD P15428 3/20 0.43
CYP1A2 P05177 2/20 0.43
HSD17B10 Q99714 2/20 0.43
GLA P06280 1/20 0.43
POLB P06746 1/20 0.43
CYP2D6 P10635 1/20 0.43
ERBB2 P04626 1/20 0.41
FYN P06241 1/20 0.41
MAOA P21397 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705735 0.91 KMT2A (0.46) MAPTKMT2AGAAMEN1TDP1
SCHEMBL2554149 0.84 GAA (0.46) MAPTKMT2AGAAMEN1TDP1
SCHEMBL15856051 0.82 ALDH1A1 (0.57) MAPTKMT2AGAAMEN1TDP1
SCHEMBL28043562 0.76 CYP1A2 (0.44) MAPTKMT2AMEN1TDP1ALDH1A1
SCHEMBL3729474 0.76 ALDH1A1 (0.45) MAPTKMT2AGAAMEN1TDP1
SCHEMBL2554146 0.75 KMT2A (0.41) MAPTKMT2AGAAMEN1TDP1
SCHEMBL183076 0.74 KMT2A (0.55) MAPTKMT2AMEN1TDP1MAOB
Pyrene SCHEMBL27607074 0.74 GAA (0.58) MAPTKMT2AGAAMEN1TDP1
SCHEMBL1666346 0.73 ALDH1A1 (0.49) MAPTKMT2AMEN1TDP1MAOB
SCHEMBL808421 0.73 MAPT (0.53) MAPTKMT2AGAAMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108414736-B Method for detecting target object by using chemiluminescence enhancer modified antibody 江苏三联生物工程有限公司 2020-11-17 CN claimed
EP-2027453-B1 NONSEPARATION ASSAY METHODS BECKMAN COULTER INC (US) 2017-03-15 EP claimed
US-8124362-B2 Nonseparation assay methods BECKMAN COULTER, INC. (US) 2012-02-28 US claimed
US-20110318747-A1 Nonseparation Assay Methods BECKMAN COULTER, INC. (US) 2011-12-29 US claimed
US-8012705-B2 Nonseparation assay methods BECKMAN COULTER, INC. (US) 2011-09-06 US claimed
US-20110183361-A1 Nonseparation Assay Methods BECKMAN COULTER, INC. (US) 2011-07-28 US claimed
EP-2027453-A4 NONSEPARATION ASSAY METHODS BECKMAN COULTER INC (US) 2009-07-01 EP claimed
EP-2027453-A1 NONSEPARATION ASSAY METHODS Beckman Coulter, Inc. (US) 2009-02-25 EP claimed
WO-2007133988-A1 NONSEPARATION ASSAY METHODS BECKMAN COULTER, INC. (US) 2007-11-22 WO claimed
US-20070264664-A1 Nonseparation assay methods NEXGEN DIAGNOSTICS LLC 2007-11-15 US claimed
CN-112400113-B Specific binding chemiluminescence assay 3M创新有限公司 2022-04-15 CN disclosed
CN-112400113-A Specific binding chemiluminescence assay 3M创新有限公司 2021-02-23 CN disclosed
CN-112400025-A Measurement of 3M创新有限公司 2021-02-23 CN disclosed
CN-108414736-B Method for detecting target object by using chemiluminescence enhancer modified antibody 江苏三联生物工程有限公司 2020-11-17 CN disclosed