SCHEMBL7057541

SCHEMBL7057541

CCCCC(N)CC(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.46
ANPEP P15144 1/20 0.46
ERAP2 Q6P179 1/20 0.46
ERAP1 Q9NZ08 1/20 0.46
TSHR P16473 2/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
NFKB1 P19838 1/20 0.44
THPO P40225 1/20 0.44
TDP1 Q9NUW8 2/20 0.42
GMNN O75496 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
PMP22 Q01453 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 2/20 0.41
MAPK1 P28482 1/20 0.41
PLA2G1B P04054 1/20 0.40
PLA2G2A P14555 1/20 0.40
SPHK1 Q9NYA1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18086852 1.00 OPRM1 (0.46) OPRM1ANPEPERAP2ERAP1TSHR
SCHEMBL18086844 1.00 OPRM1 (0.46) OPRM1ANPEPERAP2ERAP1TSHR
Hydrochloric Acid SCHEMBL6262240 0.97 TDP1 (0.46) OPRM1ANPEPERAP2ERAP1TSHR
SCHEMBL10820856 0.92 OPRM1 (0.56) OPRM1ANPEPERAP2ERAP1TSHR
Hydrochloric Acid SCHEMBL10422573 0.90 OPRM1 (0.54) OPRM1ANPEPERAP2ERAP1TSHR
Hydrochloric Acid SCHEMBL10422572 0.90 OPRM1 (0.54) OPRM1ANPEPERAP2ERAP1TSHR
SCHEMBL10754492 0.90 OPRM1 (0.54) OPRM1ANPEPERAP2ERAP1CYP3A4
SCHEMBL6287364 0.90 OPRM1 (0.54) OPRM1ANPEPERAP2ERAP1CYP3A4
SCHEMBL9853549 0.90 OPRM1 (0.54) OPRM1ANPEPERAP2ERAP1CYP3A4
SCHEMBL9202680 0.90 OPRM1 (0.54) OPRM1ANPEPERAP2ERAP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3767834-A1 ROTATING DEVICE AND ROTATING RADAR DEVICE SHENZHEN 3IROBOTIX CO., LTD. (CN) 2021-01-20 EP disclosed
EP-0994108-B1 PROCESS FOR PRODUCING 2-HYDROXYBENZAMIDE DERIVATIVES ZERIA PHARM CO LTD (JP) 2003-05-14 EP disclosed
US-6197970-B1 REACTING WITH SECONDARY OR TERTIARY AMINE; DEBLOCKING, DEPROTECTING ZERIA PHARMACEUTICAL CO., LTD. (JP) 2001-03-06 US disclosed
EP-0994108-A1 PROCESS FOR PRODUCING 2-HYDROXYBENZAMIDE DERIVATIVES ZERIA PHARMACEUTICAL CO., LTD. (JP) 2000-04-19 EP disclosed
CN-1223254-A Tertiary alkyl primary amines and process for preparing the same ROHM & HAAS (US) 1999-07-21 CN disclosed
EP-0543861-B1 IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION BRITISH BIOTECH PHARM (GB) 1998-10-14 EP disclosed
US-5276153-A Antagonist of platelet activating factor for bronchodilation BRITISH BIO-TECHNOLOGY LIMITED (GB) 1994-01-04 US disclosed
EP-0543861-A1 IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION BRITISH BIO-TECHNOLOGY LIMITED (GB) 1993-06-02 EP disclosed
US-5180723-A Hypertensives, bronchodilators, antiedemic agents BRITISH BIO-TECHNOLOGY LIMITED (GB) 1993-01-19 US disclosed
WO-1992003422-A1 BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION BRITISH BIO-TECHNOLOGY LIMITED (GB) 1992-03-05 WO disclosed