SCHEMBL70576

SCHEMBL70576

CCOC(=O)[C@H]1CC[C@@H](C(=O)OCC)S1(=O)=O

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 1/20 0.42
PTPN1 P18031 1/20 0.42
PPP1CC P36873 1/20 0.42
MAPT P10636 3/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 6/20 0.39
HSD17B10 Q99714 2/20 0.37
LMNA P02545 1/20 0.37
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7443339 0.76 L3MBTL1 (0.40) PPM1BPTPN1PPP1CCMAPTL3MBTL1
SCHEMBL1862328 0.72 L3MBTL1 (0.40) PPM1BPTPN1PPP1CCMAPTL3MBTL1
SCHEMBL2375356 0.72 MAPT (0.60) PPM1BPTPN1PPP1CCMAPTALDH1A1
SCHEMBL8891623 0.72 MAPT (0.60) PPM1BPTPN1PPP1CCMAPTALDH1A1
SCHEMBL4221 0.72
SCHEMBL6900672 0.72 PPM1B (0.47) PPM1BPTPN1PPP1CCMAPTALDH1A1
SCHEMBL10088039 0.72 PPM1B (0.47) PPM1BPTPN1PPP1CCMAPTALDH1A1
SCHEMBL6900102 0.72 PPM1B (0.47) PPM1BPTPN1PPP1CCMAPTALDH1A1
SCHEMBL1246430 0.72 PPM1B (0.47) PPM1BPTPN1PPP1CCMAPTALDH1A1
SCHEMBL237380 0.72 MAPT (0.60) PPM1BPTPN1PPP1CCMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 PPM1B 3974/4885PTPN1 3997/4885PPP1CC 4613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.