Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.63 |
| ▸ | PDE4A | P27815 | 19/20 | 0.63 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055428 | 1.00 | PDE4B (0.63) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7023689 | 0.89 | PDE4B (0.79) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL5703615 | 0.89 | PDE4B (0.79) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL5703602 | 0.89 | PDE4B (0.79) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL121198 | 0.89 | PDE4B (0.79) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6823878 | 0.89 | PDE4B (0.79) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL2480497 | 0.89 | PDE4B (0.79) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7053040 | 0.89 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL28381093 | 0.81 | PDE4B (0.92) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6820456 | 0.81 | PDE4B (0.65) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749417-B1 | CYANO COMPOUNDS AND PREPARATIONS THEREOF | SMITHKLINE BEECHAM CORP (US) | 2003-05-07 | — | — | EP | claimed |