Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 18/20 | 0.84 |
| ▸ | DRD2 | P14416 | 17/20 | 0.84 |
| ▸ | DRD4 | P21917 | 15/20 | 0.84 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.77 |
| ▸ | HTR1A | P08908 | 2/20 | 0.77 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.77 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.77 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057990 | 0.84 | DRD3 (0.78) | DRD3DRD2DRD4ADRA1AHTR1A | |
| SCHEMBL7530035 | 0.82 | DRD3 (0.79) | DRD3DRD2DRD4ADRA1AHTR1A | |
| SCHEMBL30298993 | 0.82 | DRD3 (1.00) | DRD3DRD2DRD4ADRA1AHTR1A | |
| SCHEMBL7344083 | 0.82 | DRD3 (1.00) | DRD3DRD2DRD4ADRA1AHTR1A | |
| SCHEMBL8183795 | 0.82 | DRD3 (0.94) | DRD3DRD2DRD4ADRA1AHTR1A | |
| SCHEMBL19580027 | 0.81 | DRD3 (0.79) | DRD3DRD2DRD4ADRA1AHTR1A | |
| Hydrochloric Acid SCHEMBL29634904 | 0.81 | DRD3 (0.97) | DRD3DRD2DRD4ADRA1AHTR1A | |
| Hydrochloric Acid SCHEMBL7533065 | 0.81 | DRD3 (0.93) | DRD3DRD2DRD4ADRA1AHTR1A | |
| SCHEMBL29730963 | 0.81 | DRD3 (1.00) | DRD3DRD2DRD4ADRA1AHTR1A | |
| SCHEMBL7765417 | 0.79 | DRD3 (1.00) | DRD3DRD2DRD4ADRA1AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028728-A1 | 4-(4-SUBSTITUTED PIPERAZINYL-1YL)-BUTYLCARBOXAMIDES AS D3 DOPAMINE SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |