Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.61 |
| ▸ | ECE1 | P42892 | 4/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | GLP1R | P43220 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP4 | P49662 | 1/20 | 0.44 |
| ▸ | CASP5 | P51878 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP9 | P55211 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.44 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.44 |
| ▸ | CCKAR | P32238 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7058447 | 0.95 | EDNRA (0.58) | EDNRAECE1ERAP2MMP2MMP1 | |
| SCHEMBL7261791 | 0.89 | EDNRA (0.65) | EDNRAECE1ERAP2MMP2MMP1 | |
| SCHEMBL7261793 | 0.89 | EDNRA (0.65) | EDNRAECE1ERAP2MMP2MMP1 | |
| SCHEMBL30533189 | 0.86 | EDNRA (0.73) | EDNRAECE1ERAP2MMP2MMP1 | |
| SCHEMBL30045857 | 0.86 | EDNRA (0.68) | EDNRAECE1ERAP2MMP2MMP1 | |
| SCHEMBL30533188 | 0.86 | EDNRA (0.73) | EDNRAECE1ERAP2MMP2MMP1 | |
| SCHEMBL7996597 | 0.85 | EDNRA (0.67) | EDNRAECE1ERAP2MMP2MMP1 | |
| SCHEMBL7996606 | 0.85 | EDNRA (0.67) | EDNRAECE1ERAP2MMP2MMP1 | |
| SCHEMBL6990687 | 0.85 | EDNRA (0.63) | EDNRAECE1ERAP2MMP2MMP1 | |
| SCHEMBL30533182 | 0.84 | EDNRA (0.71) | EDNRAECE1ERAP2MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772633-B1 | COMPLEXES FOR USE IN THE DIAGNOSIS OF VASCULAR DISEASES | DIAGNOSTIKFORSCHUNG INST (DE) | 2003-05-14 | — | — | EP | claimed |
| EP-0772633-B1 | COMPLEXES FOR USE IN THE DIAGNOSIS OF VASCULAR DISEASES | DIAGNOSTIKFORSCHUNG INST (DE) | 2003-05-14 | — | — | EP | disclosed |