Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.65 |
| ▸ | ECE1 | P42892 | 5/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.53 |
| ▸ | MMP2 | P08253 | 3/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | IL1RN | P18510 | 2/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.48 |
| ▸ | GLP1R | P43220 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP4 | P49662 | 1/20 | 0.46 |
| ▸ | CASP5 | P51878 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP9 | P55211 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.46 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261791 | 1.00 | EDNRA (0.65) | EDNRAECE1ERAP2MMP2MMP8 | |
| SCHEMBL30045857 | 0.95 | EDNRA (0.68) | EDNRAECE1ERAP2MMP2MMP8 | |
| SCHEMBL7996597 | 0.94 | EDNRA (0.67) | EDNRAECE1ERAP2MMP2MMP8 | |
| SCHEMBL7996606 | 0.94 | EDNRA (0.67) | EDNRAECE1ERAP2MMP2MMP8 | |
| SCHEMBL29973282 | 0.92 | EDNRA (0.56) | EDNRAERAP2IL1RNGLP1R | |
| SCHEMBL30533172 | 0.91 | EDNRA (0.61) | EDNRAECE1ERAP2MMP2MMP8 | |
| SCHEMBL30423068 | 0.90 | GLP1R (0.59) | EDNRAGLP1R | |
| SCHEMBL30533164 | 0.90 | EDNRA (0.59) | EDNRAECE1ERAP2MMP2MMP8 | |
| SCHEMBL30533188 | 0.89 | EDNRA (0.73) | EDNRAECE1ERAP2MMP2MMP8 | |
| SCHEMBL7058615 | 0.89 | EDNRA (0.61) | EDNRAECE1ERAP2MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030185757-A1 | Iron-containing nanoparticles with double coating and their use in diagnosis and therapy | KRESSE MAYK (DE) | 2003-10-02 | — | — | US | disclosed |
| CN-1103604-C | Iron-containing nanoparticles with double coating and their use in diagnostics and therapy | DIAGNOSTIKFORSCHUNG INST (DE) | 2003-03-26 | — | — | CN | disclosed |
| US-20020141943-A1 | Iron-containing nanoparticles with double coating and their use in diagnosis and therapy | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 2002-10-03 | — | — | US | disclosed |
| US-6291639-B1 | ORGAN-SPECIFIC PROBES FOR TUMOR OR INFLAMMATION IMAGING; KITS WITH RADIISOTOPES | INSTITUT FUE DIAGNOSTIKFORSCHUNG GMBH (DE) | 2001-09-18 | — | — | US | disclosed |
| US-6048515-A | MAGNETITE OR MAGHEMITE CORE; DEXTRAN COATING | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 2000-04-11 | — | — | US | disclosed |