Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.50 |
| ▸ | TYMS | P04818 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28123557 | 0.81 | MAPT (0.58) | CYP3A4L3MBTL1HIF1ACYP1A2CCR1 | |
| SCHEMBL5139016 | 0.80 | CYP3A4 (0.52) | CYP3A4CYP2A6TYMSTSHRMAPK1 | |
| SCHEMBL6321346 | 0.76 | CYP3A4 (0.52) | CYP3A4CYP2A6TYMSTSHRMAPK1 | |
| SCHEMBL10025807 | 0.76 | CYP3A4 (0.61) | CYP3A4CYP2A6TYMSTSHRMAPK1 | |
| SCHEMBL13169332 | 0.75 | MAPT (0.56) | CYP3A4CYP2A6MAPK1RAB9AL3MBTL1 | |
| SCHEMBL275514 | 0.75 | CYP3A4 (0.46) | CYP3A4CYP2A6TYMSMAPK1L3MBTL1 | |
| SCHEMBL8571951 | 0.74 | CYP1A2 (0.58) | CYP3A4CYP2A6TYMSTSHRMAPK1 | |
| SCHEMBL17532752 | 0.74 | TYMS (0.46) | CYP3A4CYP2A6TYMSTSHRMAPK1 | |
| SCHEMBL460290 | 0.74 | GPR3 (0.57) | CYP2A6RAB9ACYP1A2ALDH1A1NPC1 | |
| SCHEMBL28864050 | 0.73 | CYP3A4 (0.74) | CYP3A4CYP2A6TYMSTSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133645-A1 | RADIOLABELED COMPOUNDS FOR IMAGING OF FIBROBLAST ACTIVATION PROTEIN (FAP) AND TREATMENT OF FAP-RELATED DISORDERS | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2023-07-20 | — | — | WO | disclosed |
| WO-2003026657-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |