Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | SI | P14410 | 5/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29263804 | 0.90 | MEN1 (0.52) | MEN1KMT2AMAPTKDM4EPKM | |
| SCHEMBL29263805 | 0.90 | MEN1 (0.52) | MEN1KMT2AMAPTKDM4EPKM | |
| SCHEMBL4170824 | 0.85 | MAPT (0.54) | MEN1KMT2AMAPTKDM4EPKM | |
| SCHEMBL4184199 | 0.85 | MAPT (0.54) | MEN1KMT2AMAPTKDM4EPKM | |
| SCHEMBL1893849 | 0.85 | MEN1 (0.59) | MEN1KMT2AMAPTKDM4EPKM | |
| SCHEMBL18165412 | 0.79 | MEN1 (0.55) | MEN1KMT2AMAPTKDM4EPKM | |
| SCHEMBL6588456 | 0.79 | GPR84 (0.53) | MEN1KMT2AMAPTKDM4EPKM | |
| SCHEMBL5913085 | 0.79 | GPR84 (0.53) | MEN1KMT2AMAPTKDM4EPKM | |
| SCHEMBL195995 | 0.79 | GPR84 (0.53) | MEN1KMT2AMAPTKDM4EPKM | |
| SCHEMBL195996 | 0.79 | GPR84 (0.53) | MEN1KMT2AMAPTKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030074691-A1 | Resistance to viruses and viroids in transgenic plants and animals expressing dsRNA-binding protein | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2003-04-17 | — | — | US | disclosed |
| US-5990388-A | TRANSGENIC PLANT EXPRESSING A CLONED DNA ENCODING A VACCINIA VIRUS E3L PROTEIN AT A LEVEL TO COMPLEX AND SEQUESTER DOUBLE-STRANDED RNA-LIKE STRUCTURE OF VIRUS/VIROID; BIOLOGICAL PEST CONTROL; VIRICIDES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1999-11-23 | — | — | US | disclosed |
| EP-0832260-A2 | RESISTANCE TO VIRUSES AND VIROIDS IN TRANSGENIC PLANT AND ANIMAL HOSTS EXPRESSING dsRNA-BINDING PROTEIN | Research Corporation Technologies, Inc (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040948-A2 | RESISTANCE TO VIRUSES AND VIROIDS IN TRANSGENIC PLANT AND ANIMAL HOSTS EXPRESSING dsRNA-BINDING PROTEIN | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-12-19 | — | — | WO | disclosed |