Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | MGLL | Q99685 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | EBP | Q15125 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 5/20 | 0.32 |
| ▸ | HTT | P42858 | 4/20 | 0.32 |
| ▸ | GALR3 | O60755 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209861 | 1.00 | PTGS1 (0.34) | PTGS1PTGS2MGLLFAAHEBP | |
| SCHEMBL7055307 | 1.00 | PTGS1 (0.34) | PTGS1PTGS2MGLLFAAHEBP | |
| SCHEMBL7059088 | 1.00 | PTGS1 (0.34) | PTGS1PTGS2MGLLFAAHEBP | |
| SCHEMBL7059322 | 1.00 | PTGS1 (0.34) | PTGS1PTGS2MGLLFAAHEBP | |
| SCHEMBL7057785 | 1.00 | PTGS1 (0.34) | PTGS1PTGS2MGLLFAAHEBP | |
| SCHEMBL7059429 | 1.00 | PTGS1 (0.34) | PTGS1PTGS2MGLLFAAHEBP | |
| SCHEMBL7060655 | 1.00 | PTGS1 (0.34) | PTGS1PTGS2MGLLFAAHEBP | |
| SCHEMBL7057358 | 1.00 | PTGS1 (0.34) | PTGS1PTGS2MGLLFAAHEBP | |
| SCHEMBL7059090 | 1.00 | PTGS1 (0.34) | PTGS1PTGS2MGLLFAAHEBP | |
| SCHEMBL7060875 | 1.00 | PTGS1 (0.34) | PTGS1PTGS2MGLLFAAHEBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610278-B2 | Hardness not greater than 75 as measured by an Asker rubber-hardness tester type C1L; a porosity of at least 0.4; and an impact resistance of at least 5; excellent skin feel upon use and is not easily broken. | KAO CORPORATION (JP) | 2003-08-26 | — | — | US | disclosed |
| EP-0761202-B1 | Emulsified, water-in-oil type composition and skin cosmetic preparation | KAO CORP (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-6440429-B1 | FRESH FEEL, NONSTICKY; HIGH MOLECULAR WEIGHT HYDROPHILIC POLYSILOXANE BLOCK POLYMERS; SILICONE OILS; STABILITY | KAO CORPORATION (JP) | 2002-08-27 | — | — | US | disclosed |
| EP-0761202-A2 | Emulsified, water-in-oil type composition and skin cosmetic preparation | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |
| EP-0524612-B1 | Modified silicone containing hair cosmetic | KAO CORP (JP) | 1996-03-06 | — | — | EP | disclosed |
| US-5472689-A | Hair cosmetic composition containing a poly(N-acylalkyleneimine)-organopolysiloxane block or graft copolymer | KAO CORPORATION (JP) | 1995-12-05 | — | — | US | disclosed |
| EP-0524612-A2 | Modified silicone containing hair cosmetic | KAO CORPORATION (JP) | 1993-01-27 | — | — | EP | disclosed |
| US-5057156-A | Containing phosphorous compound | NIPPON PAINT CO., LTD. (JP) | 1991-10-15 | — | — | US | disclosed |