SCHEMBL7059429

SCHEMBL7059429

CCCCCCCCCCCCCN1C=CC=CO1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.34
PTGS2 P35354 3/20 0.34
MGLL Q99685 3/20 0.34
FAAH O00519 1/20 0.34
EBP Q15125 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
TBXAS1 P24557 1/20 0.32
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.32
NPC1 O15118 5/20 0.32
RAB9A P51151 5/20 0.32
HTT P42858 4/20 0.32
GALR3 O60755 2/20 0.32
POLB P06746 2/20 0.32
ATM Q13315 2/20 0.32
MAPK1 P28482 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
LMNA P02545 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MAPT P10636 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7209861 1.00 PTGS1 (0.34) PTGS1PTGS2MGLLFAAHEBP
SCHEMBL7055307 1.00 PTGS1 (0.34) PTGS1PTGS2MGLLFAAHEBP
SCHEMBL7059088 1.00 PTGS1 (0.34) PTGS1PTGS2MGLLFAAHEBP
SCHEMBL7059322 1.00 PTGS1 (0.34) PTGS1PTGS2MGLLFAAHEBP
SCHEMBL7059359 1.00 PTGS1 (0.34) PTGS1PTGS2MGLLFAAHEBP
SCHEMBL7057785 1.00 PTGS1 (0.34) PTGS1PTGS2MGLLFAAHEBP
SCHEMBL7060655 1.00 PTGS1 (0.34) PTGS1PTGS2MGLLFAAHEBP
SCHEMBL7057358 1.00 PTGS1 (0.34) PTGS1PTGS2MGLLFAAHEBP
SCHEMBL7059090 1.00 PTGS1 (0.34) PTGS1PTGS2MGLLFAAHEBP
SCHEMBL7060875 1.00 PTGS1 (0.34) PTGS1PTGS2MGLLFAAHEBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1128611-C Emulsified, water-in-oil type composition and skin cosmetic preparation KAO CORP (JP) 2003-11-26 CN disclosed
US-6610278-B2 Hardness not greater than 75 as measured by an Asker rubber-hardness tester type C1L; a porosity of at least 0.4; and an impact resistance of at least 5; excellent skin feel upon use and is not easily broken. KAO CORPORATION (JP) 2003-08-26 US disclosed
EP-0761202-B1 Emulsified, water-in-oil type composition and skin cosmetic preparation KAO CORP (JP) 2003-05-14 EP disclosed
US-6440429-B1 FRESH FEEL, NONSTICKY; HIGH MOLECULAR WEIGHT HYDROPHILIC POLYSILOXANE BLOCK POLYMERS; SILICONE OILS; STABILITY KAO CORPORATION (JP) 2002-08-27 US disclosed
CN-1150539-A Emulsified, water-in-oil type composition and skin cosmetic preparation KAO CORP (JP) 1997-05-28 CN disclosed
EP-0761202-A2 Emulsified, water-in-oil type composition and skin cosmetic preparation KAO CORPORATION (JP) 1997-03-12 EP disclosed
EP-0524612-B1 Modified silicone containing hair cosmetic KAO CORP (JP) 1996-03-06 EP disclosed
US-5472689-A Hair cosmetic composition containing a poly(N-acylalkyleneimine)-organopolysiloxane block or graft copolymer KAO CORPORATION (JP) 1995-12-05 US disclosed
EP-0524612-A2 Modified silicone containing hair cosmetic KAO CORPORATION (JP) 1993-01-27 EP disclosed