Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 16/20 | 0.71 |
| ▸ | NPY4R | P50391 | 4/20 | 0.71 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.71 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.61 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.61 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.57 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899864 | 1.00 | NPY1R (0.71) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL7751683 | 0.95 | NPY1R (0.62) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| Trifluoroacetic Acid SCHEMBL649618 | 0.94 | NPY1R (0.66) | NPY1RNPY4RNPY5RMCHR1 | |
| SCHEMBL8527213 | 0.94 | NPY1R (0.63) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL8636365 | 0.94 | NPY1R (0.63) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL650331 | 0.93 | NPY1R (0.72) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL7746012 | 0.93 | NPY1R (0.61) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL4651828 | 0.93 | NPY1R (0.61) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL8526741 | 0.92 | NPY1R (0.61) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL4651799 | 0.92 | NPY1R (0.61) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337257-A4 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | UNIV CALIFORNIA (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1337257-A1 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | The Regents of the University of California (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002028393-A1 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-04-11 | — | — | WO | disclosed |