Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 16/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059933 | 1.00 | ADRB3 (0.49) | ADRB3ADRB1ADRB2GLACYP1A2 | |
| SCHEMBL7059103 | 0.95 | ADRB3 (0.49) | ADRB3ADRB1ADRB2GLACYP1A2 | |
| SCHEMBL7059105 | 0.95 | ADRB3 (0.49) | ADRB3ADRB1ADRB2GLACYP1A2 | |
| SCHEMBL7051952 | 0.88 | ADRB3 (0.46) | ADRB3ADRB1ADRB2GLACYP1A2 | |
| SCHEMBL7051954 | 0.88 | ADRB3 (0.46) | ADRB3ADRB1ADRB2GLACYP1A2 | |
| SCHEMBL7055697 | 0.85 | ADRB3 (0.65) | ADRB3ADRB1ADRB2CYP1A2CYP2C9 | |
| SCHEMBL7059156 | 0.85 | ADRB3 (0.55) | ADRB3ADRB1ADRB2CYP1A2CYP2C9 | |
| SCHEMBL7059151 | 0.85 | ADRB3 (0.55) | ADRB3ADRB1ADRB2CYP1A2CYP2C9 | |
| SCHEMBL7058816 | 0.82 | ADRB3 (0.51) | ADRB3ADRB1 | |
| Hydrochloric Acid SCHEMBL7051964 | 0.82 | ADRB3 (0.50) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940387-B1 | PHENYLETHANOLAMINE COMPOUNDS USEFUL AS BETA3 AGONIST, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATES IN THE PRODUCTION OF THE SAME | MITSUBISHI PHARMA CORP (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-6069176-A | PHENYLETHANOLAMINE COMPOUNDS WITH A BETA-3 ADRENERGIC RECEPTOR STIMULATING EFFECT, USE AS A THERAPY FOR URINARY INCONTINENCE | MITSUBISHI-TOKYO PHARMACEUTICALS, INC. (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0940387-A1 | PHENYLETHANOLAMINE COMPOUNDS USEFUL AS BETA3 AGONIST, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATES IN THE PRODUCTION OF THE SAME | TOKYO TANABE COMPANY LIMITED (JP) | 1999-09-08 | — | — | EP | disclosed |