Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 15/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051952 | 1.00 | ADRB3 (0.46) | ADRB3ADRB1ADRB2GLACYP2D6 | |
| SCHEMBL7059933 | 0.88 | ADRB3 (0.49) | ADRB3ADRB1ADRB2GLACYP2D6 | |
| SCHEMBL7059932 | 0.88 | ADRB3 (0.49) | ADRB3ADRB1ADRB2GLACYP2D6 | |
| SCHEMBL7059103 | 0.85 | ADRB3 (0.49) | ADRB3ADRB1ADRB2GLACYP2D6 | |
| SCHEMBL7059105 | 0.85 | ADRB3 (0.49) | ADRB3ADRB1ADRB2GLACYP2D6 | |
| Hydrochloric Acid SCHEMBL7054734 | 0.85 | ADRB3 (0.59) | ADRB3ADRB1ADRB2GLACYP2D6 | |
| SCHEMBL7058088 | 0.83 | ADRB3 (0.43) | ADRB3ADRB1ADRB2GLA | |
| Hydrochloric Acid SCHEMBL7057667 | 0.77 | ADRB3 (0.45) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7051168 | 0.77 | OPRK1 (0.46) | ADRB3ADRB1ADRB2CYP3A4CYP2C9 | |
| SCHEMBL7051162 | 0.77 | OPRK1 (0.46) | ADRB3ADRB1ADRB2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940387-B1 | PHENYLETHANOLAMINE COMPOUNDS USEFUL AS BETA3 AGONIST, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATES IN THE PRODUCTION OF THE SAME | MITSUBISHI PHARMA CORP (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-6069176-A | PHENYLETHANOLAMINE COMPOUNDS WITH A BETA-3 ADRENERGIC RECEPTOR STIMULATING EFFECT, USE AS A THERAPY FOR URINARY INCONTINENCE | MITSUBISHI-TOKYO PHARMACEUTICALS, INC. (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0940387-A1 | PHENYLETHANOLAMINE COMPOUNDS USEFUL AS BETA3 AGONIST, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATES IN THE PRODUCTION OF THE SAME | TOKYO TANABE COMPANY LIMITED (JP) | 1999-09-08 | — | — | EP | disclosed |