Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | DRD5 | P21918 | 1/20 | 0.58 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1546830 | 0.83 | DRD2 (0.83) | ALDH1A1KMT2ALMNAGAADRD2 | |
| SCHEMBL1546828 | 0.83 | DRD2 (0.83) | ALDH1A1KMT2ALMNAGAADRD2 | |
| SCHEMBL14813507 | 0.79 | KMT2A (0.57) | ALDH1A1KMT2ALMNAGAADRD2 | |
| SCHEMBL25366560 | 0.79 | SLC18A3 (0.83) | ALDH1A1KMT2ALMNAGAADRD2 | |
| SCHEMBL19493848 | 0.79 | SLC18A3 (0.83) | ALDH1A1KMT2ALMNAGAADRD2 | |
| SCHEMBL22307922 | 0.79 | DRD2 (0.66) | ALDH1A1KMT2ALMNAGAADRD2 | |
| SCHEMBL23374660 | 0.79 | DRD2 (0.66) | ALDH1A1KMT2ALMNAGAADRD2 | |
| SCHEMBL9912160 | 0.79 | DRD2 (0.66) | ALDH1A1KMT2ALMNAGAADRD2 | |
| SCHEMBL22623899 | 0.79 | DRD2 (0.57) | ALDH1A1KMT2ALMNAGAADRD2 | |
| SCHEMBL24755587 | 0.79 | DRD1 (0.70) | KMT2ADRD2DRD3DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045509-A2 | METHOD OF USING A COX-2 INHIBITOR AND A 5-HT1A RECEPTOR MODULATOR AS A COMBINATION THERAPY | PHARMACIA CORPORATION (US) | 2004-06-03 | — | — | WO | claimed |